September 13, 2024 by Dana-Farber Cancer Institute A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial led by Dana-Farber Cancer Institute researchers, reinforce earlier...
September 12, 2024 by Ingrid Fadelli , Tech Xplore Exploded-view schematic of electronic components, a tactile sensor array, a 3D-printed mouthguard, and encapsulation structures. Credit: Hou et al.Recent technological advances have enabled the development of a wide range of electronic devices designed to improve people’s quality of life and assist them in completing their everyday...
September 12, 2024 by Brain Chemistry Labs Neurally-derived extracellular vesicles extracted from a standard blood sample contain microRNA sequences used to diagnose ALS. Credit: Paul Cox.A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects neurons in the brain and spinal cord. ALS leads to...
September 12, 2024 by Institute for Research in Biomedicine (IRB Barcelona) Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients’ response to checkpoint inhibitors (CPIs). The study, which has been published in Nature Genetics, validates these factors in more than 1,400 patients and diverse types...
September 12, 2024 by Diabetologia Credit: Unsplash/CC0 Public DomainSemaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) held in Madrid,...
September 12, 2024 by King’s College London Credit: Unsplash/CC0 Public DomainAutomated insulin delivery systems have, for the first time, been tested for people with type-one diabetes and end-stage kidney disease. The results found that they were safe and able to offer improvements in managing the patient’s blood glucose. An automated insulin delivery system (also known...
September 12, 2024 by Kim North Shine, University of Michigan Slc39a8 mediates the uptake of 54Mn at the apical membrane of intestinal organoid monolayer culture. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49049-8Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of...
News Release 12-Sep-2024 Peer-Reviewed PublicationJAMA Network Nicolas Chirpaz, MD1; Marion Bricout, MD1; Sandra Elbany, MD1; et al Retinopathy associated with the use of hair dye aromatic amines (RAHDAA) was recently reported in 3 middle-aged women following exposure to hair dyes containing aromatic amines.1 It was described as multiple bilateral serous retinal detachments (SRDs) mimicking MEK...
September 11, 2024 by Diabetologia Credit: Pixabay/CC0 Public DomainThe phase 3 SURPASS-4 trial published in 2021 established that tirzepatide lowers blood sugar and supports weight loss better than insulin glargine (a long-acting insulin) for type 2 diabetes (T2D). Now new research examining a broad range of potential predictors of sustaining blood sugar control and weight...
September 11, 2024 by British Medical Journal Credit: Unsplash/CC0 Public Domain One dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection and should be made available to communities at risk, finds a study published by The BMJ . With mpox infections rising again across the globe, the researchers...
