Month: <span>September 2024</span>

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Brain Aging Trajectories Identified in Post-Mortem Tissue
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Brain Aging Trajectories Identified in Post-Mortem Tissue

— Alzheimer’s may be driven by multicellular communities, analysis suggests by Judy George, Deputy Managing Editor, MedPage TodaySeptember 3, 2024 Key TakeawaysTwo distinct pathways of brain aging emerged in a cellular analysis of post-mortem brain tissue.One trajectory led to Alzheimer’s disease, the other to an alternative brain aging pathway.Cellular communities, not singular cell subpopulations, may...

Common food dye found to make skin and muscle temporarily transparent
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Common food dye found to make skin and muscle temporarily transparent

Researchers say procedure not yet tested on people could eventually be used to help locate injuries or tumours Ian Sample Science editorThu 5 Sep 2024 14.00 EDT Researchers have peered into the brains and bodies of living animals after discovering that a common food dye can make skin, muscle and connective tissues temporarily transparent. Applying...

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Night owls are more likely to develop type 2 diabetes – and it’s not just because of an unhealthy lifestyle, Dutch study finds

News Release 8-Sep-2024 Reports and ProceedingsDiabetologia Night owls have a higher BMI, larger waists, more hidden body fat and are almost 50% more likely to develop type 2 diabetes (T2D) than those who go to bed earlier, new research to be presented at the Annual Meeting of the European Association for the Study of Diabetes...

Brain scans reveal that mindfulness meditation for pain is not a placebo
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Brain scans reveal that mindfulness meditation for pain is not a placebo

September 5, 2024 by University of California – San Diego These brain scans show different neural signatures associated with pain response: the NAPS (left) is associated with the emotional experience of pain, the SIIPS-1 (center) is related to our expectations of pain and other psychosocial factors, and the NPS (right) is associated with pain intensity....

Innovative semaglutide hydrogel could reduce diabetes shots to once a month
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Innovative semaglutide hydrogel could reduce diabetes shots to once a month

September 7, 2024 by Diabetologia Credit: CC0 Public DomainFrench researchers have developed a new drug delivery system that could cut the dosing schedule for type 2 diabetes and weight control drug semaglutide to just once a month, according to new research to be presented at this year’s annual meeting of the European Association for the...

Insulin resistance is linked to over 30 diseases—and to early death in women, finds UK study
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Insulin resistance is linked to over 30 diseases—and to early death in women, finds UK study

September 7, 2024 by Diabetologia Credit: Pixabay/CC0 Public Domain Insulin resistance is associated with 31 different diseases, and in women, is also linked to higher odds of early death. This is according to a study of data on hundreds of thousands of people in the UK being presented at the Annual Meeting of the European...

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Alopecia Areata Linked to Psychiatric, Autoimmune Comorbidities

Medscape Medical News > MedBrief Edited by Shrabasti Bhattacharya August 01, 2024 TOPLINE:Patients with alopecia areata (AA) had a higher prevalence of several psychiatric and autoimmune comorbidities at baseline and were at greater risk of developing those comorbidities after diagnosis. METHODOLOGY:Researchers evaluated 63,384 patients with AA and 3,309,107 individuals without AA (aged 12-64 years) from...

Could Nixing a Tryptophan Metabolite Temper Alzheimer’s?
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Could Nixing a Tryptophan Metabolite Temper Alzheimer’s?

06 Sep 2024 Could one tiny little amino acid derivative make Alzheimer’s disease a whole lot worse? In the August 25 Science, researchers led by Katrin Andreasson, Stanford University School of Medicine, report that, in response to oligomers of Aβ or tau, astrocytes produce copious amounts of the tryptophan metabolite kynurenine, which scuppers glycolysis and...

Altered blood markers detected in individuals with periodontitis
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Altered blood markers detected in individuals with periodontitis

September 6, 2024 by Umea University Credit: Cedric Fauntleroy from PexelsIndividuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis and the underlying causes of the disease. Severe periodontitis affects about one in...

Alzheimer’s study reveals critical differences in memory loss progression based on the presence of specific proteins
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Alzheimer’s study reveals critical differences in memory loss progression based on the presence of specific proteins

September 6, 2024 by Karolinska Institutet Hypometabolism FDG PET patterns in the group of Aβ(+)T(-) fast decliners (14 out of 19 individuals had available FDG PET scans). Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02672-9A study from Karolinska Institutet, published in the journal Molecular Psychiatry, offers new insights into the progression of Alzheimer’s disease (AD). The research...