Month: <span>September 2024</span>

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Inhaler misuse leads to mismanagement of COPD symptoms, increased exacerbations

News Release 20-Aug-2024 Patients need additional education on proper inhaler use to improve outcomes Peer-Reviewed PublicationCOPD Foundation MIAMI (August 20, 2024) – Inhaler misuse leading to inadequate medication delivery impacts a person’s ability to manage symptoms of chronic obstructive pulmonary disease (COPD), and additional education about proper inhaler use is needed to improve health outcomes,...

The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use
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The FDA calls them ‘recalls,’ yet the targeted medical devices often remain in use

August 20, 2024 by David Hilzenrath, Kaiser Health News Credit: Unsplash/CC0 Public DomainIn 2016, medical device giant Abbott issued a recall for its MitraClip cardiac device—”a Class I recall, the most serious type,” the FDA said. “Use of this device may cause serious injuries or death,” an FDA notice about the recall said. But neither...

U.S. births continue to fall, dropping by 17% since 2007
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U.S. births continue to fall, dropping by 17% since 2007

August 20, 2024 by Ernie Mundell Final government data finds the number of U.S. births falling by 2% last year compared to 2022, continuing a decades-long decline. Overall, annual U.S. birth numbers have fallen by 17% since peaking in 2007, according to the new report from the U.S. Centers for Disease Control and Prevention. The...

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Sugar Substitutes, Originally Meant to Reduce Health Risk, May Wreak Havoc on Gut Microbiomes

Medscape Diabetes & EndocrinologyCOMMENTARY Brandy W. Root, RDN DISCLOSURES | August 16, 2024 Commercial sugar substitutes have been used since the late 1800s when saccharin was accidentally developed by a chemist at Johns Hopkins University. Due to widespread sugar rationing during World Wars I and II, saccharin grew in popularity. In more recent times, the...

ESMO: Combination therapy reduced agitated delirium in patients with advanced cancers
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ESMO: Combination therapy reduced agitated delirium in patients with advanced cancers

September 15, 2024 by University of Texas M. D. Anderson Cancer Center Credit: Unsplash/CC0 Public DomainTreatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD...

Long-term metastatic melanoma survival dramatically improves on immunotherapy, clinical trial finds
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Long-term metastatic melanoma survival dramatically improves on immunotherapy, clinical trial finds

September 15, 2024 by Weill Cornell Medical College Credit: CC0 Public DomainLong-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Weill Cornell Medicine and Dana-Farber Cancer Center investigators...

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MNT Investigates: Do ulcerative colitis treatments reduce the risk of heart attack?

Research has linked ulcerative colitis (UC) to an increased risk of heart disease, including heart attack and stroke. Some UC treatments may help reduce the risk of heart problems, though more research is necessary. UC refers to chronic inflammation in the inner lining of the large intestine. People with UC may also develop inflammation in...

RNA-sequencing study provides novel insights into chronic lymphocytic leukemia
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RNA-sequencing study provides novel insights into chronic lymphocytic leukemia

September 13, 2024 by Karolinska Institutet Long-read RNA-sequencing validates the predicted alternative transcripts related to the ncBAF complex in SF3B1-mutated CLL. Credit: Leukemia (2024). DOI: 10.1038/s41375-024-02379-4RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript abundances. One area of increasing interest is alternative splicing, a process that allows...

Researchers discover new target for treating heart failure: Protein kinase N
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Researchers discover new target for treating heart failure: Protein kinase N

September 13, 2024 by Nagoya University Protein kinase N (PKN) 1 and PKN2 are expressed in cardiac fibroblasts. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52068-0, https://www.nature.com/articles/s41467-024-52068-0As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart...

Signs of arthritis found in one in four psoriasis patients, new study reveals
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Signs of arthritis found in one in four psoriasis patients, new study reveals

September 13, 2024 by David Kearns, University College Dublin Credit: Pixabay/CC0 Public DomainOne in four participants in a European wide study aimed at detecting early signs of psoriasis showed signs of possible arthritis. This is according to the Hippocrates Prospective Observational Study (HPOS), which involves researchers at University College Dublin, in partnership with the University...