September 12, 2024 by Institute for Research in Biomedicine (IRB Barcelona) Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients’ response to checkpoint inhibitors (CPIs). The study, which has been published in Nature Genetics, validates these factors in more than 1,400 patients and diverse types...
Semaglutide and tirzepatide lead to better blood sugar control and weight loss in type 1 diabetes, study finds
September 12, 2024 by Diabetologia Credit: Unsplash/CC0 Public DomainSemaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) held in Madrid,...
Artificial pancreas shows promise in people with type 1 diabetes on kidney dialysis
September 12, 2024 by King’s College London Credit: Unsplash/CC0 Public DomainAutomated insulin delivery systems have, for the first time, been tested for people with type-one diabetes and end-stage kidney disease. The results found that they were safe and able to offer improvements in managing the patient’s blood glucose. An automated insulin delivery system (also known...
Gut reaction: Low levels of manganese can aggravate inflammatory bowel disease
September 12, 2024 by Kim North Shine, University of Michigan Slc39a8 mediates the uptake of 54Mn at the apical membrane of intestinal organoid monolayer culture. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49049-8Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of...
Retinopathy associated with hair dye
News Release 12-Sep-2024 Peer-Reviewed PublicationJAMA Network Nicolas Chirpaz, MD1; Marion Bricout, MD1; Sandra Elbany, MD1; et al Retinopathy associated with the use of hair dye aromatic amines (RAHDAA) was recently reported in 3 middle-aged women following exposure to hair dyes containing aromatic amines.1 It was described as multiple bilateral serous retinal detachments (SRDs) mimicking MEK...
Predictors for achieving, sustaining blood glucose control, weight loss with tirzepatide in adults with type 2 diabetes
September 11, 2024 by Diabetologia Credit: Pixabay/CC0 Public DomainThe phase 3 SURPASS-4 trial published in 2021 established that tirzepatide lowers blood sugar and supports weight loss better than insulin glargine (a long-acting insulin) for type 2 diabetes (T2D). Now new research examining a broad range of potential predictors of sustaining blood sugar control and weight...
One dose of smallpox vaccine found to be moderately effective in preventing mpox infection
September 11, 2024 by British Medical Journal Credit: Unsplash/CC0 Public Domain One dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection and should be made available to communities at risk, finds a study published by The BMJ . With mpox infections rising again across the globe, the researchers...
High doses of some prescription stimulants tied to increased psychosis risk
September 12, 2024 by McLean Hospital Credit: Unsplash/CC0 Public DomainPrescribing rates for stimulants that treat attention-deficit/hyperactivity disorder (ADHD) have increased significantly over the past decade, with some of the largest increases reported during the COVID-19 pandemic. A new study of adult emergency department admissions at Mass General Brigham, led by McLean Hospital researchers, found that...
How parents and caregivers can evaluate the research on MERT and other potential autism treatments
September 12, 2024 by Corinne Purtill, Los Angeles Times Credit: Unsplash/CC0 Public DomainAs diagnoses of autism spectrum disorder have increased in the last two decades, so have the number of experimental and off-label therapies seeking to address the condition. For parents navigating the complex and often contradictory landscape of autism interventions—while also balancing medical appointments,...
Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition
September 12, 2024 by Monash University Overall response time modulations in humans and in monkeys. Credit: Brain (2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has a great potential to be used in clinical practice to treat depression, anxiety and even addiction. Yet despite its widespread use in clinics and online availability for...