September 12, 2024 by King’s College London Deep learning system training schema for the 2 year prediction interval. Credit: Communications Medicine (2024). DOI: 10.1038/s43856-024-00590-zResearchers at King’s College London have used anonymized NHS eye data from more than 100,000 people with diabetes to build an AI model that can accurately predict who is at a high...
3D organoid culture method can generate large numbers of muscle cells in vitro
September 12, 2024 by Alice McCarthy, Harvard University Microscopy image of a skeletal muscle organoid. The green cells are in vitro-derived satellite cells. Credit: Feodor PriceHarvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in vitro....
Gut microbiome found to influence location of immune cells
September 12, 2024 by Max Delbrück Center for Molecular Medicine Images of the colons of conventional (left) and germ free (right) mice showing how bacterial colonization affects the distribution of immune cells along the mouse intestine. CD45 immune cells are show in red, CD3 immune cells are shown in yellow. Immune cells are concentrated close...
Insulin-free life for diabetics closer after successful cell pouch trial
Health & Wellbeing By Paul McClureSeptember 12, 2024 Transplanted cells enabled type 1 diabetics to be insulin-independent for years Depositphotos Implanting a pouch of stem-cell-derived pancreas cells under the skin of type 1 diabetics has enabled them to live without insulin injections for years and maintain non-diabetic blood sugar levels, according to the results of...
Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming
September 11, 2024 by Ingrid Fadelli , Medical Xpress Munc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson’s colocalization coefficients (c). Cultured hippocampal neurons stained with antibodies against Synapsin and Munc13-1, and a second Munc13-1 antibody or a CaV2.1 antibody. Side-view synapses were identified by...
New noninvasive technique provides effective treatment for urinary stones
September 11, 2024 by Wolters Kluwer Health Break Wave device. A, The imaging probe (left) and therapy probe (right). B, The imaging probe clicks into the center of therapy probe for treatment. C, The therapy probe and foot pedal are plugged into the therapy generator. D, The entire device required for treatment. E, An optional...
Large-scale population analysis confirms reassuring safety profile of tirzepatide
September 11, 2024by Diabetologia Credit: Unsplash/CC0 Public DomainAs more people with type 2 diabetes (T2D) are taking medications to help manage blood sugar levels and weight loss, concerns about whether these drugs are safe have emerged. Now real-world evidence from the FDA Adverse Event Reporting System (FAERS) database reveals a reassuring safety profile for tirzepatide...
Semaglutide’s cardiovascular benefits are maintained in people with impaired kidney function, research finds
September 11, 2024 by Diabetologia Credit: Pixabay/CC0 Public DomainThe anti-obesity medication semaglutide may help to prevent heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with overweight or obesity who don’t have diabetes, whether or not they also have impaired kidney function, according to new research to be...
Study reveals how antibiotics contribute to inflammatory bowel disease risk
September 11, 2024 by Bar-Ilan University Artistic interpretation of the study. The pipe represents the intestine, with antibiotics blocking the flow of mucus. Credit: DrawImpacts/Bar-Ilan University In a study published in Science Advances, Dr. Shai Bel and his research team at the Azrieli Faculty of Medicine of Bar-Ilan University have uncovered crucial insights into how...
Research team develops the prosthesis of the future, the first in the world with magnetic control
September 11, 2024 by Sant’Anna School of Advanced Studies, Pisa Experimental tests on robotic prosthesis: clothespin. Credit: 2024 Scuola Superiore Sant’AnnaIt is the first magnetically controlled prosthetic hand that allows amputees to reproduce all movements simply by thinking and to control the force applied when grasping fragile objects. No wires, no electrical connection, only magnets...