September 11, 2024 by University of Cincinnati Credit: Unsplash/CC0 Public DomainA study published in the journal Brain shows that increases in protein levels with new Alzheimer’s drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques. During a study challenging the idea that newly approved monoclonal antibodies...
Diabetes drug helps the immune system recognize reservoirs of HIV, study discovers
September 10, 2024 by Bruno Geoffroy, University of Montreal Hospital Research Centre Graphical abstract. Credit: iScience (2024). DOI: 10.1016/j.isci.2024.110670Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and eliminate it entirely in people living with HIV who receive antiretroviral therapy, Canadian researchers say in a new study. In 2021,...
Harnessing the power of placebo for pain relief: Study investigates neural circuits linked to effect
September 11, 2024 by Jennifer Michalowski, Massachusetts Institute of Technology Credit: Current Biology (2024). DOI: 10.1016/j.cub.2024.08.004 Placebos are inert treatments, generally not expected to impact biological pathways or improve a person’s physical health. But time and again, some patients report that they feel better after taking a placebo. Increasingly, doctors and scientists are recognizing that...
Small RNA molecule plays role in driving aging, research confirms
September 11, 2024 by Kendall Daniels, University of North Carolina at Chapel Hill School of Medicine The liver of miR-29TG and 2 year-old wildtype mice share changes in key aging-related genes and pathways. Credit: Communications Biology (2024). DOI: 10.1038/s42003-024-06735-zA team led by UNC School of Medicine researchers is the first to confirm that a small...
Silver nanoparticles and a new sensing method can fight back against antibiotic-resistant biofilms
Story by Rahel Collyer-Hoar Silver nanoparticles, combined with a conventional antibiotic drug and stabilized by a polymer, work together to damage the cell walls of bacteria within biofilms. Credit: National Institute of Advanced Industrial Science and Technology (AIST)From safeguarding our food supply to preventing hospital infections, the battle against antibiotic-resistant bacteria is a growing challenge....
New research provides insights into how the brain regenerates lost myelin
September 11, 2024 by Wiley Myelin sheath. Credit: Wikipedia.The neurons of the brain are protected by an insulating layer called myelin. In certain diseases like multiple sclerosis, this protective layer is damaged and lost, leading to death of neurons and disability. New research published in The FEBS Journal reveals the importance of a protein called...
Researchers uncover shared cellular mechanisms across three major dementias
September 11, 2024 by University of California, Los Angeles Credit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated “molecular markers”—observable changes in cells and their gene-regulating networks—that are shared by several forms of dementia that affect different regions of the brain. Critically, the UCLA-led research, published in the journal Cell, also identified markers...
Cheaper, highly effective oral ‘Ozempic’ drugs are on the way
By Bronwyn ThompsonSeptember 09, 2024 The race is on to get the first GLP-1 weight-loss medication onto the market Depositphotos The race is on to develop the first daily weight-loss pill that would be both cheaper and less invasive than the current injectable drugs on the market, with the latest strong trial results from US...
Aston University develops novel bone cancer therapy which has 99% success rate
News Release 10-Sep-2024 Peer-Reviewed PublicationAston University image: Professor Richard Martin Credit: Aston University Bioactive glasses, doped with gallium developed to create a potential treatment for bone cancerLab tests have a 99 percent success rate of killing cancerous cellsMethod could also regenerate diseased bones. Bioactive glasses, a filling material which can bond to tissue and improve...
Drug treatment shows promise for dangerous snoring condition, obstructive sleep apnea
News Release 10-Sep-2024 Reports and ProceedingsEuropean Respiratory Society image: Portrait of researcher Professor Jan Hedner Credit: Jan Hedner / European Respiratory Society Patients taking sulthiame, a drug currently in use for epilepsy, experienced a reduction in their symptoms of obstructive sleep apnoea (OSA), according to results of a clinical trial presented at the European Respiratory...