News Release 10-Sep-2024 Peer-Reviewed PublicationNetherlands Institute for Neuroscience – KNAW image: Infographic hallucinations Credit: Eline Feenstra – Netherlands Institute for Neuroscience A new study from the Netherlands Institute for Neuroscience shows how flickering light can cause hallucinations in our brain: it produces ‘standing waves’ of brain activity. You’re sitting on the bus or train and...
AI uncovers the secrets of human cognition
News Release 10-Sep-2024 FAU researchers gain major insights into how our brains workPeer-Reviewed PublicationFriedrich-Alexander-Universität Erlangen-Nürnberg In a pioneering study, the two scientists Dr. Patrick Krauss and Dr. Achim Schilling from the Cognitive Computational Neuroscience Group at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now used artificial intelligence to gain major insights into how our brains work that may...
2-bromopalmitate reduces senescence in human cells: Role of palmitoylation
News Release 10-Sep-2024 “For the first time, the present study revealed a critical role for protein palmitoylation in the development of a DNA damage-induced senescence phenotype.” Peer-Reviewed PublicationImpact Journals LLC image: Figure 4. The influence of 2-BP treatment on the levels of senescence markers. The levels of p-p53 (A), HMGB1 (B), and lamin B1 (C)...
Combined anti-seizure drug and omega-3 may lower COVID-19 risks
September 9, 2024 by Claire Kowalick, University of Texas Health Science Center at San Antonio Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights. Credit: PLOS ONE (2024). DOI: 10.1371/journal.pone.0307154Ronald Rodriguez, MD, Ph.D., professor of medical education and urology at Joe...
Diagnostic tool identifies puzzling inflammatory diseases in kids
September 9, 2024 by David Nutt, Cornell University Sample overview. (A) Sample counts and distribution of hospital of origin for each disease group. “Other” indicates other hospitalized pediatric controls (B) Age distribution, (C) C-reactive protein (CRP) levels, (D) sex distribution, and (E) ICU status distribution for each sample group.RNA performs a number of biological duties,...
TAAR1 gene mutations may be a missing link in understanding neuropsychiatric disorders, researchers suggest
September 9, 2024 by Genomic Press The association between TAAR1 variants, neuropsychiatric disorders, and therapeutic response. TAAR1 mutations (only selected mutations are shown for clarity) in patients with neuropsychiatric disorders (top panel). A model proposing altered signaling of trace amines in variant TAAR1 observed in neuropsychiatric disorders (bottom left). Treatment options are tailored to patients...
Urate transporter structures reveal the mechanism behind important drug target for gout
September 9, 2024 by St. Jude Children’s Research Hospital Cryo-EM structures of human URAT1 in different functional states. Credit: Cell Research (2024). DOI: 10.1038/s41422-024-01023-1Scientists at St. Jude Children’s Research Hospital have used cryo-electron microscopy to generate ten structures of URAT1, a protein linked to gout. Gout is a type of arthritis caused by excess urate...
Off-label drugs prescribed for breathlessness may do more harm than good, warn scientists
September 9, 2024 by King’s College London A new study from King’s College London shows that off-label prescriptions of a common antidepressant doesn’t help breathlessness in patients with respiratory disease—and may cause side effects. Researchers warn prescribing medicines for a use which it has not been licensed could make things worse, even though the prescriber...
Unraveling schizophrenia: New insights into genetic and environmental interplay
September 10, 2024 by Genomic Press Credit: Pixabay/CC0 Public DomainIn the complex landscape of mental health research, a new viewpoint offers a critical examination of how genes and environment conspire to influence schizophrenia risk. Published in Genomic Psychiatry, this analysis by researchers Natassia Robinson and Sarah E. Bergen from Karolinska Institutet in Stockholm, Sweden, brings...
Exploring the possible link between PTSD and early menopause
September 10, 2024 by The North American Menopause Society Credit: Unsplash/CC0 Public DomainPost-traumatic stress disorder (PTSD) can cause an array of adverse mental health effects, but physical side effects are also common. A new study conducted with Persian Gulf War female military personnel demonstrates that women with probable PTSD are twice as likely to experience...