September 10, 2024 by VIB (the Flanders Institute for Biotechnology) Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114719Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is the most common degenerative motor neuron disease in adults. It is characterized by a selective loss of motor neurons, resulting in progressive muscle weakness and paralysis, as well as...
Trauma exposure accelerates brain aging which can lead to Alzheimer’s disease, study suggests
September 10, 2024 by The North American Menopause Society Credit: Human Brain ProjectAs the median age of our population rises, so does the number of people diagnosed with Alzheimer’s disease. With advances in technology, it’s easier to determine brain age and identify blood-based Alzheimer’s disease biomarkers. A new study links trauma exposure with brain age...
Pressure sensing by muscles provides a promising new target for treatments
September 10, 2024 by Michael Dimitriou, Umea University Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114699A new study from Umeå University, Sweden, shows that the body’s muscles sense mechanical pressure. This new discovery has important implications for movement neuroscience and may improve the design of training and rehabilitation to relieve stiff muscles. The work is published in...
Scientists use AI to detect chronic high blood pressure in people’s voice recordings
September 10, 2024 by Klick Applied Science Overview of the proposed ML-based acoustic model for hypertension screening. Abbreviations: BP-blood pressure; SBP-systolic blood pressure; DBP-diastolic blood pressure; LLD-low-level descriptor; LASSO-Least Absolute Shrinkage and Selection Operator; SMOTE-Synthetic Minority Oversampling Technique. The subscripts I and F refer to initial and final measurements, respectively. Credit: IEEE Access (2024). DOI:...
Dyslexia and ADHD share genetic links, study shows
September 10, 2024 by University of Edinburgh Genetic relationships between ten neurodevelopmental and psychiatric disorders. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02649-8Scientists have shed new light on the genetic basis of dyslexia, showing how it overlaps with that of attention deficit hyperactivity disorder (ADHD). This study, led by the University of Edinburgh, is the first to...
How context-specific factors control gene activity
September 9, 2024 by Ecole Polytechnique Federale de Lausanne Credit: Pixabay/CC0 Public DomainEvery cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene regulation; essentially how and when genes are turned on...
Exciting advance in stem cell therapy
SCIENCE & TECHNOLOGY NEWS A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential. Surgery – illustrative photo. Image credit: Max Pixel, CC0 Public Domain Stem cell therapy has been heralded as a new way to treat many...
Body’s Touch Sensor Has A Previously Undiscovered Signal
SCIENCE & TECHNOLOGY NEWS The human body’s sense of touch is so important it can be found throughout the body, not just on the skin. Skin – illustrative photo. Image credit: Pixabay (Free Pixabay license) Two tiny sensors of touch, Piezo1 and Piezo2, signal the lightest pressures and can be found monitoring the circulatory system,...
Chinese Medical Journal Pulmonary and Critical Care Medicine study explores biomarkers for pulmonary fibrosis management
News Release 9-Sep-2024 The review explores how biomarkers could revolutionize the diagnosis, prognosis, and treatment of pulmonary fibrosis for enhanced patient outcomes Peer-Reviewed PublicationChinese Medical Journals Publishing House Co., Ltd. image: Biomarkers revolutionize the diagnosis and management of Idiopathic Pulmonary Fibrosis, leading to improved patient outcomes Credit: Yong Zhou of the Tulane University Image Source...
Cancer cells may be using lipids to hide from the immune system
September 9, 2024 by Katherine Fenz, Rockefeller University Glycosphingolipids (in pink, via Cholera Toxin B) are so critical for cancer immune evasion that certain cancer cells cannot proliferate without it. Credit: Rockefeller UniversityCancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags...