August 30, 2024 by Rajalaxmi Natarajan, Baylor College of Medicine Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01740-1 A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital, reveals that the protein Tau—a key player implicated in several neurodegenerative conditions including Alzheimer’s disease—also...
Dietary vitamin E may be protective against atopic dermatitis
August 30, 2024 by Lori Solomon Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in Skin Research & Technology. Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues conducted a Mendelian randomization analysis to explore the causal relationship between dietary...
Digital consultations found to improve the rate at which heart failure patients receive optimal medication
August 31, 2024 by Amsterdam University Medical Centers Credit: Unsplash/CC0 Public DomainPatients with heart failure, a condition affecting more than 60 million worldwide, are four times more likely to receive the optimal combination of medications after 12 weeks of digital consultations. Researchers from five Dutch hospitals, coordinated by Amsterdam UMC, found that the use of...
Novel low-dose 3-in-1 blood pressure pill significantly outperforms standard care, study shows
August 31, 2024 by George Institute for Global Health Credit: Pixabay/CC0 Public DomainNew research shows that a treatment plan based on a novel combination of low doses of three anti-hypertensive drugs in a single pill—known as GMRx2—was superior to a high-quality standard care treatment plan at lowering blood pressure in patients with uncontrolled hypertension. Results...
Mitochondria keep your brain cells alive: Helping them run smoothly may protect against Parkinson’s disease
August 31, 2024 by Rebecca Zhangqiuzi Fan and Kim Tieu, Florida International University Mitochondria produce the energy that fuels cells. Credit: OpenStax, CC BY-SAIn 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, Parkinson’s...
Vutrisiran offers a new lifeline to patients with progressive heart condition
August 30, 2024 by European Society of Cardiology Credit: Unsplash/CC0 Public DomainVutrisiran significantly improved mortality, cardiovascular events and markers of disease progression in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to late-breaking research presented in a Hot Line session held today, August 30, at ESC Congress 2024. “ATTR is a progressive, fatal disease in...
A new smart mask analyzes your breath to monitor your health
Caltech/Wei Gao and Wenzheng Heng Your breath can give away a lot about you. Each exhalation contains all sorts of compounds, including possible biomarkers for disease or lung conditions, that could give doctors a valuable insight into your health. Now a new smart mask, developed by a team at the California Institute of Technology, could...
Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis
August 30, 2024 by University of Tsukuba Graphical abstract. Credit: Clinical Immunology (2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in regulatory T (Treg) cells, which typically suppress immune responses, does not adequately control elderly-onset rheumatoid arthritis. In the arthritic environment, Treg cells exhibit altered metabolic activity, reduced suppressive function, and increased...
Novel pathway could lead to potential treatment for metabolic liver disease
August 30, 2024 by Hayley Mignacca, University of Massachusetts Medical School Lyz-IFNγR2−/− mice are rescued from fatty liver progression to MASH. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49633-yResearch from the lab of Jason Kim, Ph.D., professor of molecular medicine and medicine, identified a novel pathway in the progression of metabolic liver disease that could be targeted...
Study unveils novel treatment for blocking SARS-CoV-2 entry into cells
August 30, 2024 by JooHyeon Heo, Ulsan National Institute of Science and Technology Schematic image, showing the blockade of the endocytic pathway by UNI418 in SARS-CoV-2-infected cells. Credit: Experimental & Molecular Medicine (2024). DOI: 10.1038/s12276-024-01283-2In light of the ongoing threat posed by new viruses following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),...