Osteoarthritis, which causes stiff and painful joints, affects the knees most often.Credit: Dr. P. Marazzi/Science Photo Library A blockbuster weight-loss drug sharply reduces pain from obesity-related knee arthritis and improves a person’s ability to engage in activities such as walking. That’s according to a clinical trial conducted in 11 countries — the first of its kind to...
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What is SIBO? Causes, symptoms and testing
Small intestinal bacterial overgrowth (SIBO) happens when elevated bacteria are in the small intestine. Excessive bacteria here can affect digestion and absorption. Image Credit: PawelKacperek/Shutterstock.com However, bacteria can offer benefits, including: Watch the webinar: Mastering Gut Health – Understanding SIBO What causes SIBO? A common cause of SIBO is normal intestinal motility dysfunction. Slow movement...
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High-tech tracking technology streamlines drug discovery
Researchers from Osaka University develop a large-scale drug screening technique that tracks drug targets inside cells Peer-Reviewed Publication Osaka University image: Top) Drug screening with automated system for in-cell single-molecule imaging. Bottom) Diffusion coefficient of the receptor (left) and cluster formation (right) were measured from 1,000 cells. These distributions obtained by every cell changed with...
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RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus
Peer-Reviewed Publication Science China Press image: Immunofluorescent images of S100β (red, ependymal cells) in the ependyma of Nestin–Cre and Rgs22f/f;Nestin–Cre mice at P21. By staining S100β, we assessed the integrity of LV wall in Rgs22f/f;Nestin–Cre mice. Compared to control mice (Nestin–Cre), a disrupted ependymal cell layer was observed in Rgs22 cKO mice. Photo credit: Xue Pang and Lin Gu. Credit: Photo credit: Xue...
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Human proteins identified that explain inter-individual differences in functional brain connectivity
This is a step toward an understanding of the brain that ultimately describes the mechanistic basis of human cognition and behavior Peer-Reviewed Publication University of Alabama at Birmingham Jeremy Herskowitz Credit: UAB BIRMINGHAM, Ala. – A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain...
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Wearable ultrasound tech for muscle monitoring opens new possibilities in healthcare and human-machine interfaces
University of California – San Diego image: Wearable ultrasound device offers continuous, long-term monitoring of muscle activity. Credit: Muyang Lin Engineers at the University of California San Diego have developed a wearable ultrasound device that can provide long-term, wireless monitoring of muscle activity with potential applications in healthcare and human-machine interfaces. Designed to stick to...
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Two topical treatments show similar improvement in age spots on hands
Results may be ‘similar or superior’ to invasive treatments, reports Plastic and Reconstructive Surgery Peer-Reviewed Publication Wolters Kluwer Health Photoaging of the hands Credit: Plastic and Reconstructive Surgery® October 31, 2024 — Topically applied products containing human platelet extract or vitamin C provide similar improvements in age spots (photoaging) of the hands, as reported in a clinical...
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Porous dermal fillers show promise for diabetic wound treatment
Terasaki Institute for Biomedical Innovation image: (Left to Right) Principal Investigator Dr. Johnson V. John and Postdoctoral Researcher Dr. Meenakshi Kamaraj, showcasing the injectable granular filler that provides an innovative approach to diabetic wound treatment. Credit: Terasaki Institute for Biomedical Innovation Los Angeles, CA – October 31, 2024 – Researchers at the Terasaki Institute for Biomedical...
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Glaucoma drug shows promise against neurodegenerative diseases, animal studies suggest
by University of Cambridge Credit: Google DeepMind from Pexels A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer’s disease. Researchers in the UK Dementia Research Institute at the...
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Risk of post-COVID symptoms linked to body mass index in children
by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain A study by the University of Pennsylvania and researchers from 26 U.S. children’s hospitals has linked elevated body mass index (BMI) to a significantly higher risk of developing post-acute sequelae of SARS-CoV-2 infection (PASC) among children and young adults. The study revealed a 25.4% increased...