September 30, 2024 by The Mount Sinai Hospital Researchers at the Icahn School of Medicine at Mount Sinai have made a promising breakthrough in the treatment of small cell lung cancer (SCLC). Their study, published in Science Advances and titled “ATR Inhibition Activates Cancer Cell cGAS/STING-Interferon Signaling and Promotes Anti-Tumor Immunity in Small Cell Lung...
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Researchers discover mechanism driving immune perturbations after severe infections
September 30, 2024 by Taylor Barnes, Baylor College of Medicine Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated. Their findings, published in the Proceedings of the National Academy of Sciences, suggest a...
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Suicide attempts decreased after adding suicide care to primary care, study finds
September 30, 2024 by Kaiser Permanente After suicide care was integrated into routine primary care visits, researchers saw a 25% decrease in the rate of suicide attempts in the following 90 days, a new Kaiser Permanente study finds. The study, published in the Annals of Internal Medicine, is the first to show that suicide risk...
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Researchers suggest rethinking ‘cancer’ label for early-stage prostate changes
A new paper in the Journal of the National Cancer Institute indicates that patients may benefit if doctors stop calling certain early-stage changes to the prostate “cancer” at all. The paper is titled “When is prostate cancer really cancer?”. Prostate cancer is the second leading cause of cancer death worldwide in men, but far more...
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Cheek cell–based epigenetic clock allows scientists to estimate mortality risk
October 1, 2024 by Frontiers We don’t all age at the same rate. But while some supercentenarians may age exceptionally slowly due to winning the genetics jackpot, a plethora of behavioral and lifestyle factors are known to speed up aging, including stress, poor sleep, poor nutrition, smoking, and alcohol. Since such environmental effects get imprinted...
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Deep brain stimulation shows immediate improvement in arm and hand function post-brain injury, study finds
October 1, 2024 by University of Pittsburgh Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or stroke, University of Pittsburgh School of Medicine researchers report today in Nature Communications. Encouraging results from extensive tests in monkeys and humans open a path for a new...
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Common diabetes drug shows promise for treating macular degeneration
October 1, 2024 by University of Chicago Medical Center Age-related macular degeneration (AMD) is one of the leading causes of vision loss in adults over 50 in the United States. According to estimates from the National Eye Institute, approximately 11 million people in the U.S. are affected by some form of AMD, and that number...
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Radon, even at levels below EPA guideline for mitigation, is linked to childhood leukemia
October 1, 2024 by Oregon State University A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for mitigation. The research is published in Science of the Total Environment. The findings are important because there...
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Vitamin B12 Identified as a potential therapeutic agent in the prevention and treatment of acute pancreatitis
Acute pancreatitis (AP), which affects people of all ages, is one of the leading causes of hospital admission due to gastrointestinal diseases. Approximately 20% of patients develop moderate or severe acute pancreatitis, which carries extremely high mortality and disability rates. Even for those who recover, lifelong complications often follow, significantly affecting their quality of life....
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Large-scale human study finds Ozempic (or similar medications) may reduce opioid overdose risk by 40%
Credit: Pixabay/CC0 Public Domain A study published in the journal Addiction has found that people with opioid or alcohol use disorder (OUD, AUD) who take Ozempic or similar medications to treat diabetic/weight-related conditions appear to have a 40% lower rate of opioid overdose and a 50% lower rate of alcohol intoxication than people with OUD and AUD who do...