September 27, 2024 by Elana Gotkine Omitting biopsy in patients with negative magnetic resonance imaging (MRI) results is associated with a significantly reduced relative risk for detecting clinically insignificant prostate cancer, according to a study published in the New England Journal of Medicine. Jonas Hugosson, M.D., Ph.D., from Sahlgrenska Academy at the University of Gothenburg...
Post
Hydrogel with ultrasound activation enables sustained drug release
September 28, 2024 by University of Michigan Researchers at Michigan Medicine have developed a composite hydrogel capable of achieving sustained, steady drug release using ultrasound as a trigger. The team behind the breakthrough believes it could revolutionize drug delivery for various medical applications, in which constant drug levels are crucial for optimal therapeutic outcomes. The...
Post
Mouse study explores how nerve cells repair themselves
September 27, 2024 by Ohio State University Medical Center New mouse model research led by scientists at The Ohio State University Wexner Medical Center, College of Medicine and Imperial College London explored how nerve cells repair themselves, which could lead to new treatments for nerve injuries. Researchers studied how the 3D structure of DNA in...
Post
An oral weight loss pill has just passed early trials with promising results—here’s how it works
September 26, 2024 by Martin Whyte, The Conversation The arrival of GLP-1 analog drugs (such as Wegovy) marked a huge shift in the weight-loss drug market. These drugs have been shown to lead to significant weight loss in users—as much as 15% or more of their body weight in clinical trials. For this reason, demand...
Post
Cognitive deficits from meth and PCP use are generated by a common neurotransmitter switch, neurobiologists show
September 26, 2024 by Mario Aguilera, University of California – San Diego In normal mice (left), magenta neurons express the excitatory transmitter glutamate and green neurons express the inhibitory transmitter GABA. Methamphetamine (right) causes glutamate-expressing neurons to express GABA, demonstrated by neurons co-expressing magenta and green labels (arrowheads) in methamphetamine-treated mice but not in untreated...
Post
A ‘Google Earth’ view of bone—with an eye toward disease prevention
September 26, 2024 by Eric Williamson, University of Virginia Everyone knows that we can view the broad structures of our bones in the body by taking X-rays. Yet that’s just scratching the surface. Science now has a host of new imaging and characterization techniques to go deeper, and define more narrowly, the architecture and relative...
Post
Synthetic compound shows promise against drug-sensitive, drug-resistant strains of human malaria parasites
September 26, 2024 by University of California – Riverside This photomicrograph of a blood smear contains a macro- and microgametocyte of the Plasmodium falciparum parasite. In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite. For decades, the parasite’s resistance to all...
Post
Researchers discover new bacterium that causes gut immunodeficiency
September 26, 2024 by Cleveland Clinic Cleveland Clinic researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, Tomasiella immunophila (T. immunophila), which plays a key role in breaking down a crucial immune component of the gut’s...
Post
World’s first individual gene mutation test for predicting risk of sudden cardiac death
September 26, 2024 by Victor Chang Cardiac Research Institute Scientists at the Victor Chang Cardiac Research Institute, working with colleagues at the Vanderbilt University Medical Center, have developed a world-first, individualized risk prediction tool for people suffering from a type of heart arrhythmia that can cause sudden cardiac arrest. This is the first time a...
Post
New research confirms link between perceived stress and psoriasis relapse
September 26, 2024 by European Academy of Dermatology and Venereology Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo. Psoriasis, a chronic...