Medscape Medical News > Conference News > EASD 2024 Nancy A. Melville September 19, 2024 MADRID — The benefits of semaglutide treatment in reducing kidney disease, cardiovascular, and mortality risks in people with type 2 diabetes and chronic kidney disease (CKD) are observed regardless of whether patients are also being treated with mineralocorticoid receptor antagonists...
Month: <span>October 2024</span>
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Review of performance measures for pain finds those for acute pain treatment lacking
September 24, 2024 by American College of Physicians Credit: CC0 Public DomainA review by the American College of Physicians (ACP) of performance measures designed to evaluate quality of care for those adults suffering from pain found three of six measures relevant to internal medicine physicians to be valid. “Quality Indicators for Pain in Adults: A...
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Fibrosis lacks treatments and methods of reversal: Study pinpoints a promising target for drug therapy
September 23, 2024 by Delthia Ricks , Medical Xpress Model of MERTK mechanisms for regulating TGFβ core fibrotic pathway across various organs. Credit: Science Translational Medicine (2024). DOI: 10.1126/scitranslmed.adj0133Medical science has long been on the hunt for a deeper understanding of the devastating scarring of the body’s organs known as fibrosis, which leads to irrevocable...
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New study shows durability of minimally invasive procedure to combat knee pain
September 23, 2024 by Society of Interventional Radiology Credit: Journal of Vascular and Interventional Radiology (2024). DOI: 10.1016/j.jvir.2024.08.028A new study shows that a minimally invasive treatment for osteoarthritis (OA) in the knees may have a lasting benefit of at least 2 years. Published today in the Journal of Vascular and Interventional Radiology during Pain Awareness...
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Scientists uncover limits of metabolic flexibility in squamous cell skin cancer
September 23, 2024 by Ani Vahradyan, University of California, Los Angeles Microscopy image of a squamous cell carcinoma, stained with glutamine transporter (ASCT2, green) and nuclei (DAPI, blue). This tumor lacks the enzyme LDHA, which normally helps cells process glucose. Credit: William Lowry Lab/UCLAScientists at the Eli and Edythe Broad Center of Regenerative Medicine and...
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Neuroscientists discover complex genetic programs at the root of our movements
September 23, 2024 by University of Geneva The image shows corticospinal neurons in a mouse brain. Credit: Philipp Abe and Advanced Lightsheet Imaging Center Campus BiotechA UNIGE team has discovered the genetic programs that allow motor neurons to retract from the spinal cord. This discovery opens up prospects for combating neurodegeneration. The motor cortex is...
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Certain antidepressants may improve brain function, study finds
September 23, 2024 by European College of Neuropsychopharmacology Credit: Wikimedia CommonsResearchers have found that SSRI (selective serotonin reuptake inhibitor) antidepressants have the potential to improve certain cognitive functions, such as verbal memory. They measured brain function in patients before and after taking the SSRI, escitalopram, and correlated this to a drop in the level of...
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Researchers ‘turbocharge’ vaccine delivery by jolting ‘bystander’ immune cells into action in animal models
September 23, 2024 by Monash University Credit: Immunity (2024). DOI: 10.1016/j.immuni.2024.08.017Monash University researchers have developed a new technique to boost the effectiveness of both traditional and mRNA-based vaccines in animal models. Published in Immunity, the study found that adding low doses of a vaccine-specific antibody to a COVID-19 vaccine stimulated the immune system’s B cells,...
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Understanding sex-specific differences in aortic aneurysms
September 23, 2024 by University of Kentucky Graphical abstract. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI169085A group of researchers at the University of Kentucky have found a mechanism that would explain why men develop more aortic aneurysms than women. The study titled “Androgen aggravates aortic aneurysms via suppression of PD-1 in mice,” accompanied by...
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Innovative model using CRISPR provides valuable insights into prostate cancer spread
September 23, 2024 by Weill Cornell Medical College Abstract representation of the cancer clonal landscapes in different places in the body, revealing the different clonal architectures. The lines represent some of the trajectories of metastatic cells as they traverse the body. Credit: American Association for Cancer ResearchA new preclinical model using CRISPR, an advanced technology...