Month: <span>October 2024</span>

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Study: Referral to hepatology is lower in patients with excessive alcohol use who have mental health disorders
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Study: Referral to hepatology is lower in patients with excessive alcohol use who have mental health disorders

September 23, 2024 by Research Society on Alcoholism Credit: Pixabay/CC0 Public DomainPeople with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of...

Small-molecule drug shows potential for hard to treat cancers
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Small-molecule drug shows potential for hard to treat cancers

September 23, 2024 by University of Dundee Credit: Unsplash/CC0 Public DomainExperts from the University of of Dundee’s Centre for Targeted Protein Degradation (CeTPD), working with Boehringer Ingelheim scientists, have developed a breakthrough small-molecule drug, a “protein degrader.” KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions...

B-cells hold promise for treating glioblastoma
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B-cells hold promise for treating glioblastoma

September 23, 2024 by Olivia Dimmer, Northwestern University Quantitative analysis of BCR-seq data. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI177384Harnessing the body’s B-cells to fight tumors may be a promising treatment for glioblastoma, according to a Northwestern Medicine study recently published in the Journal of Clinical Investigation. Glioblastoma, one of the most complex and...

Study shows psilocybin gives comparable long-term antidepressant effects to standard antidepressants
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Study shows psilocybin gives comparable long-term antidepressant effects to standard antidepressants

September 21, 2024 by European College of Neuropsychopharmacology Credit: CC0 Public DomainA direct comparison between the experimental psychedelic drug psilocybin and a standard SSRI antidepressant shows similar improvement of depressive symptoms, but that psilocybin offers additional longer-term benefits. The comparison, between psilocybin (the active ingredient in “magic mushrooms”) and the SSRI escitalopram gave similar long-term...

More than half of people who use party drugs take ADHD medicines without a prescription, new research shows
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More than half of people who use party drugs take ADHD medicines without a prescription, new research shows

September 22, 2024 by Rachel Sutherland, Amy Peacock, Caroline Salom, Jodie Grigg and Raimondo Bruno, The Conversation Credit: Alex Green from PexelsEach year, the National Drug and Alcohol Research Center at UNSW Sydney surveys hundreds of people who regularly use drugs in Australia to understand trends in substance use around the country. Today, we’ve released...

Tiny plastic grains that are injected into your knee – and can end agony of arthritis in the knee
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Tiny plastic grains that are injected into your knee – and can end agony of arthritis in the knee

By Erin Dean For The Mail On Sunday Published: 19:25 EDT, 21 September 2024 | Updated: 20:28 EDT, 21 September 2024 Injecting tiny grains of plastic into the knee joint could offer hope to patients crippled by arthritis pain, NHS research suggests. The ground-breaking technique requires only a local anaesthetic, a few hours in hospital...

Analysis sheds light on COVID-19-associated disease in Japan
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Analysis sheds light on COVID-19-associated disease in Japan

September 20, 2024 by Osaka Metropolitan University The invasive fungal infection pulmonary aspergillosis is caused by the aspergillus fungus and has been known to occur among patients with COVID-19. Credit: Yukihiro Kaneko, Osaka Metropolitan UniversityAs society learns to live with COVID-19, research on the disease and its complications remains important. Thus, an Osaka Metropolitan University...

Study shows bariatric surgery outperforms GLP-1 diabetes drugs for kidney protection
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Study shows bariatric surgery outperforms GLP-1 diabetes drugs for kidney protection

September 20, 2024 by Cleveland Clinic Credit: Pixabay/CC0 Public DomainA Cleveland Clinic study showed that in patients with type 2 diabetes, obesity, and chronic kidney disease, bariatric surgery was associated with a significant decrease in the progression of chronic kidney disease compared to those who received GLP-1 diabetes medications. The paper was published in Annals...

New migraine drugs no better than cheap painkillers: big study
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New migraine drugs no better than cheap painkillers: big study

September 21, 2024 Credit: Unsplash/CC0 Public DomainNew, more expensive migraine drugs are no more effective against the throbbing headaches than traditional painkillers, and even performed worse than an older range of treatments called triptans, said a massive global analysis Thursday. Migraines are severe, often disabling headaches which affect at least one in seven adults globally,...

Super-activation of vitamin A signaling system protects against motor neuron disease, other conditions
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Super-activation of vitamin A signaling system protects against motor neuron disease, other conditions

September 20, 2024 by University of Aberdeen Possible neuroprotective effects of ellorarxine. Credit: Frontiers in Neuroscience (2024). DOI: 10.3389/fnins.2024.1422294Drugs that “switch on” vitamin A in the body may also help stave off conditions such as motor neuron disease (MND). New research from the University of Aberdeen published today in Frontiers in Neuroscience, found, for the...