By Tina Reed Illustration: Gabriella Turrisi/Axios Federal regulators are confronting a new twist in drug development: manufacturers that include software with the medicine to prod patients to take pills as directed, manage side effects or track how well a treatment works.Why it matters: The apps could boost the drugs’ clinical value and provide a more personalized...
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Just Call It ‘Chronic Rhinitis’ and Reach for These Treatments
Matthew F. Watto, MD: I’m Dr Matthew Frank Watto, here with my great friend and America’s primary care physician, Dr Paul Nelson Williams. Paul, are you ready to talk about rhinitis? Paul N. Williams, MD: I’m excited. It’s always the season to talk about rhinitis. Watto: We had a great guest for this podcast, Rhinitis and Environmental Allergies with...
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New research shows a link between inflammatory bowel disease and joint problems
by Örebro Universitet Credit: Pixabay/CC0 Public Domain There is a strong connection between inflammatory bowel disease (IBD) and spondyloarthritis—a condition that causes pain and stiffness in the joints. The risk is particularly high among patients with Crohn’s disease and those who were diagnosed with IBD as children. Sarita Shrestha has shown this in her doctoral thesis at...
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Stroke patients could benefit from earlier blood thinning treatment, finds research
by Poppy Tombs, University College London Time-to-event curves of the primary composite outcome of recurrent ischaemic stroke, symptomatic intracranial haemorrhage, unclassifiable stroke, or systemic embolism at 90 days. Credit: The Lancet (2024). DOI: 10.1016/S0140-6736(24)02197-4 People with atrial fibrillation (AF) who have a stroke could benefit from blood thinning treatments, known as anticoagulants, at an earlier stage than is...
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New miRNA inhibitor could extinguish the ‘inflammatory fire’ that stroke causes in the brain
by University of Connecticut Novel gamma PNA based miRNA-141-3p inhibitors (syPNA-141) reduced brain damage (image on right with less atrophy) after stroke in mouse model of ischemic stroke. Credit: Verma laboratory It’s been more than three decades, but still there are only two treatments for a stroke: either rapid use of a clot-busting medication called tPA...
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Study finds no link between prenatal cannabis use and autism
by Elana Gotkine Prenatal cannabis use is not associated with child autism spectrum disorder (ASD) or with child early developmental delays, according to two studies published online Oct. 18 in JAMA Network Open. Lyndsay A. Avalos, Ph.D., M.P.H., from Kaiser Permanente Northern California in Pleasanton, and colleagues examined the association between maternal cannabis use in early pregnancy and...
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Empagliflozin offers lasting cardiorenal benefit in CKD patients
by Elana Gotkine Empagliflozin continues to offer cardiorenal benefits for up to 12 months after discontinuation among patients with chronic kidney disease at risk for progression, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held from...
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AI-based method shows promise for pathological diagnosis of hereditary kidney diseases
by University of Tsukuba Credit: The American Journal of Pathology (2024). DOI: 10.1016/j.ajpath.2024.10.004 Alport syndrome is a genetic disorder associated with kidney dysfunction, sensorineural hearing loss, and ocular abnormalities. In the kidneys, hematuria occurs in the early stages of the disease, followed gradually by proteinuria and, ultimately, end-stage renal failure, which requires renal replacement therapy such as dialysis...
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How light tells you when to sleep, focus and poo
by Frederic Gachon and Benjamin Weger, The Conversation Credit: Unsplash/CC0 Public Domain Exposure to light is crucial for our physical and mental health, as this and future articles in the series will show. But the timing of that light exposure is also crucial. This tells our body to wake up in the morning, when to poo and the...
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Don’t skip colonoscopy for new blood-based colon cancer screening, study says
by Stanford University Medical Center Credit: Karolina Grabowska from Pexels Newly available blood tests to screen for colorectal cancer sound far more appealing than a standard colonoscopy. Instead of clearing your bowels and undergoing an invasive procedure, the tests require only a simple blood draw. But are the tests effective? A study led by researchers at...