by Taylor & Francis Credit: Unsplash/CC0 Public Domain A large population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world’s most common heart valve disease—aortic stenosis (AS). Published in the Annals of Medicine, the findings are believed to be the first to highlight this previously unrecognized...
Post
Disruption of mechanical signaling in brain could be basis for development of Alzheimer’s disease, study proposes
by University of Liverpool A concept model of mechano-homeostasis and dyshomeostasis leading to whole-scale synaptic changes. Credit: Open Biology (2024). DOI: 10.1098/rsob.240185 A new study from the University of Liverpool represents a significant step forward in scientists’ understanding of Alzheimer’s disease. Researchers have shed new light on how mechanical signaling in the brain is disrupted and could lead...
Post
Cellular traffic congestion in chronic diseases suggests new therapeutic targets
by Whitehead Institute for Biomedical Research Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Whitehead Institute Member Richard Young and colleagues have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of...
Post
Researchers reveal how aging impairs antitumor activity of CD8⁺ T cells
by Chinese Academy of Sciences Working model of aging compromise CD8+ T cell-mediated antitumor immunity. Credit: Prof. Xiao’s group A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed that aging specifically impairs the generation of CD8+ tissue resident memory T cells (TRM) and thus compromises the antitumor...
Post
Drinking plenty of water helps with a variety of conditions from obesity to migraines, researchers find
by University of California, San Francisco Credit: Unsplash/CC0 Public Domain Public health recommendations generally suggest drinking eight cups of water a day. And many people just assume it’s healthy to drink plenty of water. Now researchers at UC San Francisco have taken a systematic look at the available evidence. They concluded that drinking enough water can...
Post
Greater patient education needed around antidepressants that may reduce genital sensitivity, study finds
by Jeff Hodson, Simon Fraser University Credit: Pixabay/CC0 Public Domain The use of antidepressants is associated with sexual side effects including reduced genital sensitivity that persists after stopping the medication, a new Simon Fraser University study finds. The study, published in Social Psychiatry and Psychiatric Epidemiology, indicates that 13% of people who used antidepressants reported a reduction in genital...
Post
Should postmenopausal women eat soy? Researchers dispel myth about soy and cancer
by Betty Zou, University of Toronto Credit: CC0 Public Domain A University of Toronto study is providing reassuring evidence about the consumption of soy foods in women who are postmenopausal. The analysis of 40 randomized controlled trials in over 3,000 participants found that estrogen-like compounds in soy had no effect on key markers of estrogen-related cancers,...
Post
Hyperbaric oxygen might be effective treatment for PTSD—here’s how it works
by Anders Kjellberg, The Conversation Credit: Pixabay/CC0 Public Domain Post-traumatic stress disorder (PTSD) is common in military veterans but can affect anyone who has suffered or witnessed an extreme physical or emotional event, and it is very hard to treat. More than two-thirds of people fail to respond to treatment with drugs and therapy. Novel treatments are urgently...
Post
AI algorithm can identify metabolic dysfunction-associated steatotic liver disease
by Lori Solomon An algorithm can identify individuals with metabolic dysfunction-associated steatotic liver disease (MASLD) with about 88% accuracy using electronic medical record (EMR) data, according to a study presented at The Liver Meeting, the annual meeting of the American Association for the Study of Liver Diseases, held from Nov. 15 to 19 in San Diego. Ariana...
Post
Integrative cognitive behavioral therapy for prolonged grief beats present-centered therapy
by Elana Gotkine For patients with prolonged grief disorder (PGD), integrative cognitive behavioral therapy for prolonged grief (PG-CBT) is superior to present-centered therapy (PCT) after treatment, according to a study published online Nov. 13 in JAMA Psychiatry to coincide with the European Grief Conference, held from Nov. 11 to 13 in Dublin. Rita Rosner, Ph.D., from the Catholic University Eichstätt-Ingolstadt...