Precision diagnostics for diseases that affect the brain and other organs brought closer by new ability to exclusively access contents of organ-derived extracellular vesicles in blood Peer-Reviewed Publication Wyss Institute for Biologically Inspired Engineering at Harvard image: The team’s overall goal was to be able to compare the amounts of α-synuclein protein contained in extracellular...
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Study shows how education, occupation and wealth affect the risk of cognitive impairment
by University College London Credit: Pixabay/CC0 Public Domain Socioeconomic factors such as education, occupation, and wealth influence the likelihood of developing cognitive impairment or dementia in later life and whether a person is likely to recover, finds a new study led by UCL researchers. The research, published in Scientific Reports, followed 8,442 adults aged 50 and above...
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Total hip replacement superior to resistance training for reducing hip pain, improving function
by Elana Gotkine Total hip replacement results in superior reduction in hip pain and improved hip function at six months compared with resistance training among patients aged 50 years or older with severe hip osteoarthritis and an indication for surgery, according to a study published in the Oct. 31 issue of the New England Journal of Medicine. Thomas...
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Low sugar intake in utero and in early childhood found to significantly reduce risk of midlife chronic disease
by University of Southern California Credit: Unsplash/CC0 Public Domain A low-sugar diet in utero and in the first two years of life can meaningfully reduce the risk of chronic diseases in adulthood, a new study has found, providing compelling new evidence of the lifelong health effects of early-life sugar consumption. Published in Science, the study finds that children who...
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Delayed Meniere disease tied to higher prevalence of bilateral disease
by Lori Solomon Delayed Meniere disease (DMD) is associated with a higher prevalence of bilateral Meniere disease (MD) compared with classic MD (CMD), according to a study published online Oct. 15 in the European Archives of Oto-Rhino-Laryngology. Suming Shi, from the Affiliated Eye and ENT Hospital at Fudan University in Shanghai, and colleagues investigated the clinical characteristics and...
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Examining apixaban vs aspirin in patients with cancer and cryptogenic stroke
by Ochsner Health System Credit: Pixabay/CC0 Public Domain Ochsner Health physicians Dr. Richard Zweifler and Dr. Joseph Tarsia are co-authors on a post hoc analysis carried out in the ARCADIA randomized clinical trial, comparing the effectiveness of apixaban versus aspirin in preventing adverse clinical outcomes in patients with a history of cancer and cryptogenic stroke....
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Researchers solve medical mystery of neurological symptoms in kids
by Marta Wegorzewska, Washington University School of Medicine Researchers at WashU Medicine collaborated with an international team of doctors and scientists to identify the cause of a rare disorder involving intellectual disability and brain malformations. Brain scans from a patient with this disorder reveal atypical features in white matter (arrows, left) and the cerebellum (arrows, right)....
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Fibrils study fills in a missing piece for neurodegenerative disease research
by University of Michigan Atomistic interactions between polyP and α-Syn fibrils. Credit: PLOS Biology (2024). DOI: 10.1371/journal.pbio.3002650 Research led by the University of Michigan has provided compelling evidence that could solve a fundamental mystery in the makeup of fibrils that play a role in Alzheimer’s, Parkinson’s and other neurodegenerative diseases. The research team reports its findings in the journal PLOS Biology....
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Study identifies 51 amyotrophic lateral sclerosis-associated mutations that could help diagnose the disease
by Luciana Constantino, FAPESP Credit: Pixabay/CC0 Public Domain Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle atrophy and paralysis. Thirteen of the mutations increased the risk of ALS, while 38 were protective. The study suggests these mutations may be important...
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Physician discusses advances in minimally invasive kidney stone surgery
by DeeDee Stiepan, Mayo Clinic Credit: Pixabay/CC0 Public Domain Most small kidney stones can pass on their own. However, kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract infections may require surgical treatment. Dr. Aaron Potretzke, a Mayo Clinic urologist in Rochester, Minnesota, explains some...