Month: <span>November 2024</span>

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Repurposing semaglutide and liraglutide for alcohol use disorder

JAMA PsychiatryPeer-Reviewed Publication JAMA Network About The Study: Among patients with alcohol use disorder (AUD) and comorbid obesity/type 2 diabetes, the use of semaglutide and liraglutide were associated with a substantially decreased risk of hospitalization due to AUD. This risk was lower than that of officially approved AUD medications. Semaglutide and liraglutide may be effective in...

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Psychedelic use linked to increased risk of schizophrenia, study finds

Peer-Reviewed Publication Institute for Clinical Evaluative Sciences image:  Infographic: Myran et al. JAMA Psych. 2024view more  Credit: ICES Ottawa, ON, November 13, 2024 – Individuals with emergency department visits involving hallucinogen use are at high risk of developing schizophrenia, according to a new study from researchers at ICES, The Ottawa Hospital, University of Ottawa’s Department of Family...

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New weight loss drug target burns energy and lowers appetite – without the nausea and vomiting

Peer-Reviewed Publication University of Copenhagen – The Faculty of Health and Medical Sciences Scientists at the University of Copenhagen have discovered a new weight loss drug target that reduces appetite, increases energy expenditure, and improves insulin sensitivity without causing nausea or loss of muscle mass. The discovery was reported in the journal Nature and could lead to...

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Key influenza-severity risk factor found hiding in plain sight on our antibodies

Antibody composition shapes flu severity Peer-Reviewed Publication Stanford Medicine Sialic acid (blue links) at the end of sugar chains attached to antibodies (red) induce the antibodies to bind to receptors (light blue) that promote an anti-inflammatory response in alveolar macrophages. When sialic acid is absent, the sugar chains attach to receptors (yellow) that promote inflammation,...

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Human stem cell-derived heart cells are safe in monkeys, could treat congenital heart disease

Peer-Reviewed Publication University of Wisconsin-Madison image:  Heart muscle cells grown from human induced pluripotent stem cells (in green) have successfully integrated into rhesus macaque heart muscle in this microscope image of heart tissue from a new study by UW–Madison and Mayo Clinic researchers.view more  Credit: Photo courtesy Emborg Lab / UW–Madison MADISON — Heart muscle cells...

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New discovery may lead to more effective treatment for cardiovascular disease

Case Western Reserve-led study identifies molecule that simulates inflammation-reducing effects of a low-fat dietPeer-Reviewed Publication Case Western Reserve University image:  Andrei Maiseyeuview more  Credit: Case Western Reserve University CLEVELAND—Researchers at Case Western Reserve University have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack....

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A step toward safer X-rays with new detector technology

Peer-Reviewed Publication American Chemical Society image:  A new X-ray detector produces a high-quality radiograph that shows a metal needle (top right) and the interior of a USB drive (bottom right) using lower doses of electromagnetic radiation than previous detectors.view more  Credit: Adapted from ACS Central Science 2024, DOI: https://doi.org/10.1021/acscentsci.4c01296 X-rays are a common component of diagnostic testing...

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The Puzzling Thyroid Panel: Answers to Tough Questions

Earlier this fall, Medscape Medical News spoke to endocrinologists Angela M. Leung, MD, and Karen Tsai, MD, on how to interpret abnormal results of thyroid hormone tests. To address some additional questions, we turned to Jenna S. Mammen, MD, PhD, an associate professor in the Division of Endocrinology, Diabetes and Metabolism at Johns Hopkins University in Baltimore. The interview...

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How to treat a sore tongue

Tongue soreness can be widespread or occur on one or both sides of the tongue. Treatments will largely depend on the cause, but may include good oral hygiene, mouth rinses, or certain medications. A person can treat a sore tongue with some simple home remedies. However, certain health conditions may trigger tongue pain, and these...

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Artificial sensory cilia can monitor internal biomarkers to detect and assess airway diseases

by Vanderbilt University Credit: Vanderbilt University Xiaoguang Dong, assistant professor of mechanical engineering at Vanderbilt University, is leading a team of researchers that has developed a system of artificial cilia capable of monitoring mucus conditions in human airways to better detect infection, airway obstruction, or the severity of diseases like cystic fibrosis (CF), chronic obstructive pulmonary...