by Julia Evangelou Strait, Washington University School of Medicine Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Glioblastoma is one of the...
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Why Do I Have So Much Earwax? 5 Things That Could Be Causing Your Earwax Buildup
Written by Meredith Grace Merkley, DO, FAAP | Reviewed by Christine Giordano, MD Updated on August 14, 2024print_outlinedemail_outlined Key takeaways: /iStock via Getty Images Plus If you’ve ever had an ear blocked with earwax, also called a cerumen impaction, you might be wondering what you can do to keep yourself from getting another one. Or maybe you’ve just noticed...
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What Are the Risks of Leaving a Urinary Tract Infection (UTI) Untreated?
Written by Maria Robinson, MD, MBA | Reviewed by Farzon A. Nahvi, MD Updated on August 19, 2024print_outlinedemail_outlined Key takeaways: Table of contents Definition Risks Symptoms Resolution Signs of improvement Untreated UTI FAQs Bottom line References Common Concerns About UTIs (Urinary Tract Infections) 0 seconds of 3 minutes, 25 secondsVolume 90% 03:25 Featuring Preeti Parikh, MD, Stacia Woodcock, PharmD Reviewed...
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Dog Stroke Symptoms to Watch Out For
Written by JoAnna Pendergrass, DVM | Reviewed by Ghanasyam Bey, DVM Updated on April 8, 2024 Key takeaways: Table of contents Dog stroke symptoms Life expectancy after a stroke What to do Diagnosis Treating dog strokes Dog stroke causes Bottom line References kali9/E+ via Getty Images Dogs and humans can experience many of the same health conditions, including...
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Biomarker identified for predicting inflammatory bowel disease treatment success
by Charité – Universitätsmedizin Berlin Multimodal characterization of patients with IBD receiving anti-integrin α4β7. Credit: Gastroenterology (2024). DOI: 10.1053/j.gastro.2024.09.021 Not everyone responds equally well to treatments for inflammatory bowel disease (IBD). What will work for individual patients involves trial and error during the treatment process. Now, a team of researchers led by Charité—Universitätsmedizin, in collaboration with colleagues in...
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Inhibiting specific protein action could lead to precision therapy for some patients with drug-resistant leukemia
by Duke-NUS Medical School Leukemia cells with the BIM variation under a microscope. Such cells often don’t respond well to imatinib, a common type of drug used to treat the disease, but when an MCL-1 inhibitor is added, treatment is more effective with more cancer cells being killed. Credit: Duke-NUS Medical School Scientists from Duke-NUS Medical...
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Analysis of clinical trial reveals how psilocybin could be part of treatment for anorexia nervosa
by Genomic Press Download Credit: Unsplash/CC0 Public Domain In an exploration of psychedelic medicine’s potential for treating one of psychiatry’s most challenging conditions, researchers at University of California, San Diego (UCSD) have provided an analysis and further details of a trial published in Nature Medicine that showed how psilocybin therapy affects individuals with anorexia nervosa. In an article in Psychedelics, the...
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Q&A: How a ‘switchable’ CAR-T therapy sets its sights on deadly brain cancer
by Laura López González, University of California, San Francisco Killer T cells (green and red) surround a cancer cell (blue, center). Credit: NIH UC San Francisco treated its first brain cancer patient with an experimental new CAR-T therapy discovered and manufactured at the university earlier this year. The treatment, known as E-SYNC, is a form of...
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Pancreatic incidentaloma: incidental findings from history towards the era of liquid biopsy.A promising future in pancreatic incidentaloma detection
Peer-Reviewed Publication First Hospital of Jilin University image: On the unenhanced CT of the abdomen and pelvis (A, D), no kidney or ureteral stones are identified. As an incidental finding, discrete peripancreatic fat stranding is present around the pancreatic head which leads to an effacing of the normal parenchymal contour (short open arrow in (A))....
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What if you eat nanoplastics? A laboratory exploration of their gastrointestinal digestion
In a laboratory set-up simulating the human stomach and intestine, researchers at the University of Amsterdam have explored the fate of plastic nanoparticles during gastrointestinal digestion. In a paper in the October issue of Chemosphere, they report how a range of model plastic nanoparticles interact with digestive enzymes and form agglomerates. Their exploratory findings indicate, among...