Month: <span>November 2024</span>

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A genetic key to understanding mitochondrial DNA depletion syndrome

Researchers identify a novel genetic cause of a rare mitochondrial disorder, revealing mechanisms for improved diagnosis and treatment Peer-Reviewed Publication Juntendo University Research Promotion Center image:  Identifying MICOS10 variants enhances our understanding of mitochondrial function and genetic diagnosis in rare diseasesview more  Credit: Yasushi Okazaki from Juntendo University, Japan Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic...

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Scientists find why tamoxifen works better for some people

Peer-Reviewed Publication American Society for Microbiology Highlights: Washington, D.C. — Nov. 25, 2024 — A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug. The finding, published in the journal mBio of the American Society for Microbiology, suggests that in the future, doctors...

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UTIs are extraordinarily common but kidney infections are not—now doctors know why

by Delthia Ricks , Medical Xpress NETs and UMOD entrap UPEC in vivo. Credit: Science Translational Medicine (2024). DOI: 10.1126/scitranslmed.adh5090 Infections in the lower urinary tract rarely migrate to the kidneys, but the precise mechanism that the human body employs to keep the twin organs disease-free has remained a medical mystery—until now. A multidisciplinary team at Cambridge...

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Clinical microbiologist explains why you should never kiss a baby

by Primrose Freestone, The Conversation Credit: Unsplash/CC0 Public Domain There is a cognitive bias called “the curse of knowledge” (sometimes also called “the curse of expertise”). It happens when you incorrectly assume that everyone knows as much as you do on a given topic. As a clinical microbiologist, I assumed everyone knew that it was a...

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Study finds vaping causes immediate effects on vascular function

by Radiological Society of North America Infographic for research on how vaping causes immediate effects on vascular function. Credit: Radiological Society of North America (RSNA) Researchers have identified acute effects of cigarette and e-cigarette smoking on vascular function, even without nicotine. The results of the ongoing research are being presented at the annual meeting of the Radiological Society...

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Common thyroid medicine linked to bone loss

by Radiological Society of North America Bone density scan (DEXA scan). Credit: Radiological Society of North America (RSNA) and Elena Ghotbi, M.D. Levothyroxine, the second most commonly prescribed medication among older adults in the U.S., may be associated with bone loss, according to a study being presented at the annual meeting of the Radiological Society of North America...

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A new clock to structure sleep: Study shows brain stem region involved in organization of sleep

by University of Lausanne Locus coeruleus (LC) activity patterns across wakefulness, NREMS and REMS. Credit: Alejandro Osorio-Forero et al Researchers at the University of Lausanne have identified a novel role for the brain’s “locus coeruleus” in sleep and its disruptions. This brain region facilitates the transition between NREM and REM sleep states while maintaining an unconscious...

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FDA approves Nerivio for migraine treatment in children aged 8 years and older

by Lori Solomon The U.S. Food and Drug Administration has expanded the age indication for Theranica’s Nerivio, making it the first and only remote electrical neuromodulation (REN) wearable for migraine treatment for children aged 8 years and older. The approval marks the first FDA-cleared, nondrug therapy for acute treatment of migraine in children and the...

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Stroke guidelines updated, with focus on women and GLP-1s

by Carole Tanzer Miller Women, especially those who had high blood pressure during pregnancy or entered menopause before age 45, are among those with a greater risk for stroke. They and other high-risk groups are the focus of new stroke prevention guidelines from the American Heart Association and American Stroke Association. The guidelines also suggest new GLP-1 weight-loss drugs...