by Ghent University Longitudinal images of an affected joint. Credit: Nature Medicine, DOI: 10.1038/s41591-024-02822-0Researchers at Ghent University Hospital, Ghent University, and VIB-UGent Center for Inflammation Research, show that antibody therapy can be effective against erosive hand osteoarthritis. Using the antibody denosumab leads to bone remodeling and the prevention of erosive joint damage. This is the first...
by University of Birmingham AML-subtype specific gene expression and chromatin accessibility is established in LSCs. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45691-4The mystery of why myeloid leukemia starts to grow again after chemotherapy has killed the bulk of malignant cells, and how growth may be blocked by repurposed drugs, has potentially been solved through new research. The...
by Bob Yirka , Medical Xpress Helical mCR with articulated magnetic tip. (A) The helical protrusion on the outer surface of the continuum robot, upon rotation, pushes the robot tip forward. (B) The segmented articulating magnetic tip increases the magnetic volume and decreases bending stiffness for improved steerability. (C) The helical robot prevents buckling and...
by Elana Gotkine For patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weighted lesions, according to a study published in the Feb. 15 issue of the New England Journal of Medicine.Patrick Vermersch, M.D., Ph.D., from the University of Lille in France, and colleagues...
by British Medical Journal Credit: Unsplash/CC0 Public DomainWalking or jogging, yoga and strength training seems to be the most effective exercises to ease depression, either alone or alongside established treatments such as psychotherapy and drugs, suggests an evidence review published by The BMJ. Even low-intensity activities such as walking or yoga are beneficial, but the results...
by Tessa Roy, University of Michigan Increased fibroblast synthetic activity as early as 1 week post-filler injection. Following injection of vehicle (saline) and filler (cross-linked hyaluronic acid, CL-HA) into photodamaged skin of individuals over 60 years-old, skin samples were obtained in a paired manner at 1, 2, 3 and 4 weeks. Credit: Experimental Dermatology (2024). DOI: 10.1111/exd.14998Chronic exposure of...
by University of Michigan Credit: Pixabay/CC0 Public DomainAn Achilles tendon rupture typically means surgery for many patients. A research team led by Laurence Ge, M.D., an orthopedic surgery resident mentored by Paul Talusan, M.D. at University of Michigan Health, looked at the difference in outcomes of those treated with and without surgical procedures for their Achilles...
Peer-Reviewed Publication MAYO CLINIC With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules. When a person is young, the immune system responds and eliminates senescent cells, often referred to as zombie cells. However, zombie cells linger and contribute to various age-related health problems and diseases....
Bertrand Herer, MD For researchers involved with sleep disorders, developing a pharmacologic treatment for obstructive sleep apnea (OSA) is a bit like searching for the holy grail. P K Schweitzer and colleagues have published the results of the randomized MARIPOSA study assessing a combination of two medicinal products known as AD109, one of the products...
Liz Szabo Erica Finkelstein-Parker planned her daughter’s 8th birthday party with love. Because Emmalee adored airplanes, Finkelstein-Parker chose the theme “Flying High with Emmalee.” Finkelstein-Parker filled nearly two dozen brightly colored goody bags for Emmalee’s friends — one for every child in her class, so no one would feel left out. Months later, the treat...
