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Brain Drain – Nasopharyngeal Lymphatics Found to be Crucial for Cerebrospinal Fluid Outflow
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Brain Drain – Nasopharyngeal Lymphatics Found to be Crucial for Cerebrospinal Fluid Outflow

‘Lymphatic plexus’ behind the nose drains cerebrospinal fluid from the brain, potentially impacting neurodegenerative conditions – In a groundbreaking study published in Nature, South Korean researchers led by Director KOH Gou Young of the Center for Vascular Research within the Institute for Basic Science (IBS) have uncovered a distinctive network of lymphatic vessels at the...

CSF Cerebrospinal Fluid
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CSF Cerebrospinal Fluid

IntroductionCerebrospinal fluid (CSF) is a clear, plasma-like fluid (an ultrafiltrate of plasma) that bathes the central nervous system (CNS). It occupies the central spinal canal, the ventricular system, and the subarachnoid space. Image 1 shows a 3D image of the CSF circulation as it would look inside the skull. CSF performs vital functions including: Support;...

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Why Do GLP-1 Drugs Stop Working, and What to Do About It?

There’s no question that glucagon-like peptide 1 (GLP-1) agonists represent a major advance in the treatment of obesity for patients with or without diabetes. In clinical trials, participants lost 15%-20% of their body weight, depending on the drug. But studies also have shown that once people stop taking these drugs — either by choice, because...

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Direct Measurement of T3 Is Likely Vital, Say Researchers

Marlene Busko To assess thyroid function, clinicians typically determine blood levels of thyroid-stimulating hormone (TSH) and thyroxine (T4) and do not directly measure triiodothyronine (T3). However, findings from a large observational study of a US sample of adults with normal thyroid function suggested that subclinical variation in the hypothalamic-pituitary-thyroid (HPT)–axis effector hormone T3 “is an...

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COVID, No Matter the Severity, Linked With Urologic Effects in Men

Marcia Frellick SARS-CoV-2 infection is linked in men with increased incidence of urinary retention, urinary tract infection (UTI), and blood in the urine, a new study finds. Authors of the study, led by Alex Qinyang Liu, of S.H. Ho Urology Centre, at The Chinese University of Hong Kong, highlighted the clinical implications. “Clinicians should be...

CMS Okays Payment for Novel AI Prostate Test
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CMS Okays Payment for Novel AI Prostate Test

Howard Wolinsky Editor’s note: An earlier version of this story erroneously stated that Medicare has started covering use of the AI-based cancer test. Neither the company nor CMS provided Medscape with information on how much the payment will be should the agency agree to cover the test. Medicare has set a payment rate for an...

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Ascidian’s lab in Boston is developing a new kind of RNA editing therapy

First-ever RNA editing trial in US gets clearance, pitting ‘exon editing’ technology against vision lossRyan CrossSenior Science CorrespondentThe FDA told the Boston startup Ascidian Therapeutics that it can begin the first clinical tests of a therapy that “rewrites” RNA to correct roughly two-thirds of the genetic typos responsible for an inherited form of vision loss...

Do you need to see a doctor for that rash?
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Do you need to see a doctor for that rash?

by Robin Foster When should you worry about a rash? Rashes may look alike, but while over-the-counter medications can treat some rashes, others can signal a more serious condition, the American Academy of Dermatology (AAD) says. “It is important to watch your symptoms closely at the onset of a new rash,” said Dr. Mallory Abate,...