by University of Chicago DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in Nature Genetics, combines data...
By Dr. Chinta SidharthanJan Reviewed by Lily Ramsey, LLMIn a recent study published in Communications Biology, a team of scientists investigated how type 2 diabetes and genetic susceptibility to the disease impacted the severity of and mortality risk associated with coronavirus disease 2019 (COVID-19) using data from the United Kingdom (U.K.) Biobank. Study: Type 2...
by University of Tsukuba Credit: Unsplash/CC0 Public DomainAllogeneic hematopoietic stem-cell transplantation (allo-HSCT) can cure hematopoietic diseases, such as acute myeloid leukemia. Cord blood transplantation (CBT), which accounts for more than one-third of allo-HSCTs in Japan, uses hematopoietic stem cells contained in the blood in the umbilical cord and placenta. Moreover, it is a valuable option for...
by Noah Fromson, University of Michigan Jacob Dwyer, Justine Ross / Michigan MedicineThe death rate for patients with functional, non-epileptic seizures is higher than expected, with a rate comparable to epilepsy and severe mental illness, a Michigan Medicine-led study finds. A team of researchers reviewed data from 700 patients who were diagnosed with functional seizures, also...
by Massachusetts Eye and Ear Infirmary Senior study author Nazlee Zebardast, MD, MSc, director of Glaucoma Imaging at Mass Eye and Ear, examines OCT images. Credit: Mass Eye and EarThe retina is said to provide a window into a person’s systemic health. In a new study published January 24 in Science Translational Medicine, physician-researchers from Mass...
by City of Hope National Medical Center Researchers at City of Hope and Translational Genomics Research Institute (TGen) have developed and tested an innovative machine-learning approach that could one day enable the earlier detection of cancer in patients by using smaller blood draws. The study was published today in the journal Science Translational Medicine. Credit: TGenResearchers...
by Robin Foster The U.S. Food and Drug Administration has told drugmakers to add a boxed warning to a type of cancer treatment called CAR-T therapy, saying the treatment itself may sometimes cause a secondary cancer. Still, FDA spokesperson Carly Kempler told NBC News that, despite the new warning, “the overall benefits of these products...
by Ludwig Maximilian University of Munich Pathway synopsis (I.) Sterile inflammation triggers the activation of a subset of cDCs, which respond by releasing CCL17. (II.) In turn, CCL17 binds to CCR8 on cDCs (autocrine) and on CD4+ T cells (paracrine) to stimulate an upregulation of CCL3 expression and release. (III.) Subsequently, CCL3 interacts with CCR1 on...
The finding, published in the Journal of Neuroscience, could have implications for improving memory and relieving traumatic memories.Peer-Reviewed Publication VIRGINIA TECH (FROM LEFT) RESEARCH SCIENTIST KAYLA FARRELL AND ASSOCIATE PROFESSOR TIM JAROME IN THE SCHOOL OF ANIMAL SCIENCES ARE PART OF A VIRGINIA TECH RESEARCH TEAM THAT DISCOVERED A NEW FUNCTION FOR A COMMON PROTEIN...
Commentary in the Journal of Neuromuscular Diseases provides an independent, unbiased assessment of the body of research on vamorolone Peer-Reviewed Publication IOS PRESS The drug vamorolone (Agamree®) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD). It has recently been approved for clinical use in the United States by the...
