In a new study, researchers report that health professionals who lost weight without starting a diet or exercise plan within the previous two years had a significantly higher risk of developing cancer within the following year.Upper gastrointestinal tract, hematologic, colorectal, and lung cancers were more common in people with rapid unexpected weight loss.Experts say people...
Year: <span>2024</span>
Post
Detecting bowel cancer without a stool test
by South Australian Health and Medical Research Institute (SAHMRI) Schematic of orally-delivered EcN probiotic engineered to lyse and produce immunotherapeutic proteins in situ (top) and schematic of dosing regimen (bottom). Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-44776-4An international team of researchers from Adelaide and the United States has opened the door to non-stool-based bowel cancer detection...
Post
Chemotherapy becomes more efficient when senescent cells are eliminated by immunotherapy, shows study
by Institute for Research in Biomedicine (IRB Barcelona) Senescent human melanoma tumor cells. In brown, the PD-L2 protein acts as a protective shield and prevents the action of the immune system. Credit: IRB BarcelonaCancer treatments, including chemotherapy, in addition to killing a large number of tumor cells, also result in the generation of senescent tumor cells...
Post
Protein TDP-43 keeps genetic zombies at bay: New insights into neurodegenerative disease mechanisms
by Quinn Eastman, Emory University Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2023.113662A new Cell Reports paper from Bing Yao’s lab in Emory’s Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer’s. It can be summarized in one line: TDP-43 keeps genetic zombies at bay....
Post
Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers
by Will Cushman, University of Wisconsin-Madison This image shows the effect of pro-inflammatory cytokines on the growth of a mouse intestinal organoid. Intestinal stem cells (red) are indicative of inflammation and Ki67 proteins (green) are associated with tumors. Credit: Ting FuInflammation in the gut can trigger a doom loop of sorts. The condition messes with the...
Post
Cognitive behavioral therapy alters brain activity in children with anxiety, study shows
by National Institutes of Health Credit: Tima Miroshnichenko from PexelsResearchers at the National Institutes of Health have found overactivation in many brain regions, including the frontal and parietal lobes and the amygdala, in unmedicated children with anxiety disorders. They also showed that treatment with cognitive behavioral therapy (CBT) led to improvements in clinical symptoms and brain...
Post
Researchers develop new technology for monitoring atrial fibrillation
by Kaunas University of Technology Smart wrist-worn device developed by Lithuanian scientists. Credit: KTUResearchers from two Lithuanian universities have developed a patient-safe monitoring technology to identify and manage individual factors provoking atrial fibrillation. The technology is a result of a collaboration between Kaunas University of Technology Biomedical Engineering Institute (KTU BMEI) and Vilnius University (VU) Santaros...
Post
What causes brain cell death in Alzheimer’s disease?
A study offers new clues on a potential cause of neuron death in Alzheimer’s disease. Jose A. Bernat Bacete/Getty ImagesAbout 32 million people globally have Alzheimer’s disease.While scientists are still unclear as to the true cause of Alzheimer’s disease, they do know a loss of neurons in the brain plays an important role.A new study...
Post
Systematic analysis of the prognostic value and immunological function of LTBR in cancer
by Impact Journals LLC Validation of expression of the LTBR gene. Credit: Aging (2024). DOI: 10.18632/aging.205356A new research paper titled “Systematic analysis of the prognostic value and immunological function of LTBR in human cancer” has been published in Aging. Lymphotoxin beta receptor (LTBR) is a positive T cell proliferation regulator gene. It is closely associated...
Post
Treating loneliness in the obese may lower risk of early death
by Robin Foster Loneliness can be a killer, but it can be particularly deadly for obese people, who are markedly more likely to experience social isolation. Fortunately, a new study shows that addressing it may lower the risk of health complications and early death for these folks. “To date, dietary and lifestyle factors are the...