by Elana Gotkine For patients with severe eosinophilic asthma controlled on bevacizumab, tapering of inhaled corticosteroids (ICS) is feasible and is not associated with worse asthma control, according to a study published online on Dec. 7 in The Lancet. David J. Jackson, M.P.H., from King’s College London, and colleagues conducted a phase 4 study involving...
Year: <span>2024</span>
SGLT2 Inhibitors Begin to Show Therapeutic Potential in Rheumatology
Over just a decade, sodium-glucose cotransporter-2 (SGLT2) inhibitors have revolutionized the second-line treatment of type 2 diabetes by improving the control of blood sugar, and they’re also being used to treat heart failure and chronic kidney disease. Now, there’s growing evidence that the medications have the potential to play a role in the treatment of...
Mental illness in patients with chronic kidney disease
by Karolinska Institutet Credit: Unsplash/CC0 Public DomainChronic kidney disease (CKD) affects more than 10% of adults worldwide. Mental health is an important yet under-recognized issue in patients with CKD. Depression is common and related to poor prognosis in CKD patients, but previous research has primarily focused on dialysis patients, leading to an insufficient understanding of depression...
Study provides insights into depression via ophthalmology
by Anke Schlee, Max Planck Society A high-speed camera provides information on pupil size. Credit: Martin Otter MPI PsychiatryScientists from the Max Planck Institute of Psychiatry measured the pupillary reaction of participants while they were solving a task. In healthy participants, the pupils dilated during the task in anticipation of a reward, but this reaction was...
Smartphone app could help prevent falls in older adults
by Binghamton University Weekly workout programs and example exercise instruction set with images as displayed to participants in the smartphone-based intervention group. Credit: Sensors (2023). DOI: 10.3390/s23177451Researchers at Binghamton University, State University of New York’s Motion Analysis Research Laboratory have developed an app to help study and prevent falls in older adults. Their research is published...
A novel approach for lymph node metastasis treatment
by Tohoku University Osmotic pressure-and-viscosity-modified Docetaxel via lymphatic drug delivery system (LDDS) can inhibit tumor growth in the lymphatic system and prevent distant metastasis. Increases in osmotic pressure and viscosity lead to significant tumor inhibition in the sentinel lymph node (LN) and its’ downstream LN. Moreover, we found the underlying mechanism of increased osmotic pressure and...
Is This the Cure for Restless Legs?
George Lundberg, MDDISCLOSURES I don’t rightly remember when I first learned of restless legs syndrome (RLS). It was many decades ago, and I recognized that once in a while, I would be restless during sleep, tossing and turning, seeking a favorable sleeping position. I felt like I just needed to move my legs around; my...
Can This Common Herb Help Grow Hair?
Jay Croft If you’re looking to grow hair, you might just have a solution in your kitchen cabinet — if TikTok and some dermatologists are correct. Rosemary oil is good at regrowing hair in people with androgenetic alopecia, which is a common form of hair loss. The herb might also protect hair from the sun,...
Brain structure predicts treatment response to antidepressant and placebo medications, finds study
by King’s College London Neuroanatomical patterns across the dimensions. False discovery rate- (FDR-) corrected voxel-wise comparison of gray-matter volume differences in Dimension 1 (top row) and Dimension 2 (bottom row) versus controls are presented in transverse, sagittal, and coronal sections. Color bar indicates strength of group differences (MIDAS statistic) between MDD and healthy control participants. Credit:...
Researchers discover compound that fights leukemia and lymphoma
by University of Texas at El Paso Renato Aguilera, Ph.D., a professor in the Department of Biological Sciences at The University of Texas at El Paso, is the principal investigator on a project that identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy....