by Sarah Small, Pennsylvania State University Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a lengthy and expensive trial process to prove both safety and effectiveness. By repurposing already-approved drugs, researchers can cut out the time and expense of the former step—sometimes. According to...
by Katie Neith, City of Hope National Medical Center Hope researchers discovered that ILC2s can attack cancer cells. Credit: City of HopeAccording to preclinical research published in Cell researchers at City of Hope have discovered that a type of immune cell in the human body known to be important for allergy and other immune responses can...
By Rich Haridy New research reveals impaired oxygen absorption and mitochondrial dysfunction in muscle cells may explain why exercise makes long COVID patients feel worseDepositphotos One of the most consistently reported symptoms of long COVID is the tendency for strenuous exercise to make the condition worse. Not only does long COVID reduce a person’s capacity for...
Physicians rely on algorithms for personalized medicine — but an analysis of schizophrenia trials shows the tools fail to adapt to new data sets. Miryam Naddaf Scans showing brain activity during speech for a person with schizophrenia (bottom) and one without (top).Credit: Wellcome Centre Human Neuroimaging/Science Photo Library Computer algorithms that are designed to help...
By Paul McClure Researchers have developed a peptide (orange) that targets the MYC protein (gray ribbons) to slow cancer progressionMin Xue/UC Riverside Researchers have developed a peptide that targets a previously ‘undruggable’ protein implicated in more than 75% of human cancers and found that it slowed the proliferation of brain cancer cells in the lab. It’s...
ADHD prescriptions surged among adults during the COVID-19 pandemic compared to prior years. Milko/Getty ImagesAdult prescriptions for ADHD medication surged during the COVID-19 pandemic compared to prior years, a new study reports.Other categories of drugs, including benzodiazepines, medications to treat opioid use disorder, and antidepressants, continued along regular trends or remained flat.The increase in ADHD...
by Sichuan International Medical Exchange and Promotion Association The Tat-SIRT5-CTM peptide specifically blocked the interaction of SIRT5 with ANXA1, led to SIRT5 degradation and thereby inhibiting SIRT5-mediated desuccinylation of ANXA1, which in turn alleviated microglia-induced neuroinflammation, and eventually improved the survival of neurons subjected to cerebral ischemia and reperfusion injury. Credit: Figure was drawn using...
by Elana Gotkine Two doses of recombinant zoster vaccine (RZV) are effective against herpes zoster (HZ), with the vaccine effectiveness (VE) of two doses waning a little over four years of follow-up, according to a study published online on Jan. 9 in the Annals of Internal Medicine. Ousseny Zerbo, Ph.D., from Kaiser Permanente Northern California...
by Elana Gotkine For patients with knee osteoarthritis (KOA), microfragmented adipose tissue (MFAT) injection with arthroscopic surgery is associated with improved midterm clinical outcomes, according to a study published online Dec. 26 in the World Journal of Stem Cells. Cong-Zi Wu, from the First Affiliated Hospital of Zhejiang Chinese Medical University in Hangzhou, and colleagues...
by Rietie Venter, The Conversation Credit: Pixabay/CC0 Public DomainEveryone seems to have a different opinion when it comes to how often towels and bed sheets should be washed. While many people might wonder whether days or weeks is best, in one survey from the United Kingdom, almost half of single men reported not washing their sheets...
