By Paul McClure Researchers have developed an intranasal COVID-19 vaccine that offers longer, better protection than injections Depositphotos Researchers have developed an intranasal COVID-19 vaccine that enhances the immune system’s response to the virus, providing longer-lasting, greater protection than vaccine injections, even against new and emerging variants. The novel vaccine candidate could mean fewer boosters in...
by Columbia University Irving Medical Center Graphical abstract. Credit: Immunity (2023). DOI: 10.1016/j.immuni.2023.11.003The microbiome has a profound influence on our health, but exactly how our resident bacteria wield their power is still unclear. A type of T cell appears to provide some answers for gastrointestinal health, a study of the mouse microbiome finds. The study, appearing...
By Paul McClure Researchers have found that RSV, very common in children, can also infect and damage nerve tissue Depositphotos Thought only to infect the respiratory tract, new research has proved for the first time that the respiratory syncytial virus (RSV), very common in young children, can also penetrate nerve cells directly, triggering excessive inflammation and...
by Georgia Gowing, Macquarie University Dr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can nearly double patients’ life expectancy. The new immunotherapy is a combination of two drugs—enfortumab vedotin (EV) and pembrolizumab—delivered by infusion, and it is now being submitted to regulatory...
by Tulane University Transmission electron micrograph of RSV. Credit: CDC/ Dr. Erskine Palmer / Public DomainRespiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study. RSV can cause mild symptoms such as coughing, sneezing and...
by University of Missouri Credit: Andrea Piacquadio from PexelsResearchers at the University of Missouri School of Medicine have uncovered a link between irritable bowel syndrome (IBS) and somatic disorders, such as fibromyalgia and chronic fatigue syndrome. IBS is a disorder of the stomach and intestines affecting up to 15% of the population. It causes cramping, abdominal...
by Society for Cardiovascular Angiography and Interventions Kaplan–Meier curve of 12-month freedom from binary restenosis after femoropopliteal endovascular intervention using angiography (blue) and intravascular ultrasound (IVUS) + angiography (red) in a single-center randomized trial. Reprinted with permission from Allan et al, 2022. Credit: Journal of the Society for Cardiovascular Angiography & Interventions (2024). DOI: 10.1016/j.jscai.2023.101205Proceedings from...
by Texas Heart Institute Design of injectable hydrogel electrode. Redox initiation reaction of polyether urethane diacrylamide (PEUDAm) macromer + N-acryloyl glycinamide (NAGA) delivered using double barrel syringe with a mixing head. Ammonium persulfate (APS) and iron gluconate (IG) are used as initiator and reducing agents. Resulting hydrogels display bidentate hydrogen bonding at netpoints for improved...
by Zehan Yu, Duke-NUS Medical School Mucosal vaccination protects hamsters from SARS-CoV-2-induced clinical disease. (a) Diagram of the experimental design where hamsters were vaccinated with S-RBD and M7 via various routes using a prime (day 0) and boost (day 14). Credit: eBioMedicine (2023). DOI: 10.1016/j.ebiom.2023.104924A team of scientists, led by Duke-NUS Medical School, has discovered a...
by Kayt Sukel, Rice University Scan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the immunostaining of c-Fos, an endogenous protein whose production is heightened by increased neuronal activity. Credit: Szablowski lab/Rice UniversityThe brain is the most protected organ...
