by University of Cambridge Credit: Professor Rebecca Fitzgerald/University of CambridgeA man from Cambridge is the first to join the surveillance part of a clinical trial that could see routine screening for esophageal cancer introduced into the NHS, potentially halving deaths from this cancer every year. The capsule sponge, known as the pill-on-a-thread, is a quick and...
These supposedly “bad” carbs might offer benefits in blood sugar management A woman buys vegetables at a supermarket in Buenos Aires, Argentina on August 31, 2018. — ReutersContrary to common misconceptions, not all carbohydrates are off-limits for individuals managing diabetes. A dietitian sheds light on five supposedly “bad” carbs that might offer benefits in blood...
By Rich Haridy Research indicates newer COVID variants stemming from BA.2.86 can infect the lungs more effectively than any variant since Delta Depositphotos A newly published study from researchers at Ohio State University has found the recently emerged BA.2.86 variant of SARS-CoV-2 has a greater propensity for infecting certain lung cells than any prior Omicron variant....
US biotech firm designs cheaper, less invasive multi-cancer screening test it says could be ‘gamechanger’ Andrew Gregory Health editorScientists have developed a simple DNA test that can identify 18 early-stage cancers that experts say could represent a medical “gamechanger”. Cancer accounts for one in every six deaths worldwide, but early detection can significantly improve outcomes....
F. Perry Wilson, MD, MSCE DISCLOSURES Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. When you stub your toe or get a paper cut on your finger, you feel the pain in that part of your body. It...
Medication people with type 2 diabetes use to manage their blood sugar also appear to protect their hearts and kidneys, according to a new study in JAMA Network Open. These pills, known as sodium-glucose cotransport protein 2 (SGLT2) inhibitors, reduce the amount of blood sugar in a kidney by causing more glucose to be excreted...
by Isabella Backman, Yale University Vitamin B12 intake, absorption and metabolism, and the etiologies of vitamin B12 deficiency (image created by Tova Gardin using Biorender.com). Credit: BMJ Case Reports (2023). DOI: 10.1136/bcr-2023-254727Nitrous oxide is readily accessible to those who want to use it recreationally for the high it can provide. With just a few clicks, it...
by Inka Väth, University Hospital Bonn EPAC1 signaling promotes BAT growth and function in vivo. Credit: Nature Cell Biology (2024). DOI: 10.1038/s41556-023-01311-9Brown fat cells convert energy into heat—a key to eliminating unwanted fat deposits. In addition, they also protect against cardiovascular diseases. Researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Area “Life &...
by UT Southwestern Medical Center Effect of risperidone and risperidone + LepAb on body weight, food intake, and glucose tolerance. Female mice (n = 9) were placed on an HFD alone (Ctrl) or an HFD supplemented with risperidone. Mice were treated with either control IgG or LepAb twice weekly. Body weight and food intake were measured. Glucose...
by Albert Ludwigs University of Freiburg Identification of a bi-substrate inhibitor of KMT9. a Chemical structure of compound 1a with predicted binding mode. b MST assay to determine the dissociation constant (Kd) of compound 1a and SAM binding to KMT9. c FTSA for compound 1a binding to KMT9. d Chemical structure of SAM. e FTSA for...
