by Technical University Munich Intestinal tissue during a graft-versus-host reaction: Donor cells (red) attack the body of the patient. Credit: Sebastian Jarosch, Dirk Busch / TUMAfter stem cell transplantation, the donated immune cells sometimes attack the patients’ bodies. This is known as graft versus host disease or GvHD. Researchers at the Technical University of Munich (TUM)...
Year: <span>2024</span>
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Psychologists face challenges of increased demand, patient severity
by Lori Solomon The ongoing mental health crisis is causing significant challenges for many psychologists as they grapple with both heightened demand and patients presenting with increasingly severe symptoms, according to the results of a survey released Dec. 5 by the American Psychological Association. The 2023 Practitioner Pulse Survey was emailed to a random sample...
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Targeting the mRNA of ‘undruggable’ proteins in the fight against Parkinson’s disease
by Justin Jackson , Medical Xpress Pixabay/CC0 Public DomainResearchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synuclein protein levels by targeting the mRNA that forms them. The strategy unlocks many research doors with potential therapeutic approaches for addressing neurodegenerative diseases. In a paper, “Decreasing the intrinsically disordered protein α-synuclein...
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Could a drug prevent hearing loss from loud music and aging?
Peer-Reviewed PublicationUNIVERSITY OF CALIFORNIA – SAN FRANCISCO Could a Drug Prevent Hearing Loss from Loud Music and Aging?Researchers have found a gene that links deafness to cell death in the inner ear in humans – creating new opportunities for averting hearing loss. A person’s hearing can be damaged by loud noise, aging and even certain...
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Over-the-Counter Hearing Aids: Are They Right for You?
Written by Karen Hovav, MD, FAAP | Reviewed by Sophie Vergnaud, MD Key takeaways: You can buy over-the-counter (OTC) hearing aids without a prescription or hearing test.OTC hearing aids are good for people who are older than 18 years with self-perceived mild to moderate hearing loss. This means you don’t need to have your hearing...
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Cannibalistic cells could provide an edge in future cancer treatments
By Paul McClure Researchers have added an active Rac2 protein to macrophages, causing them to cannibalize other immune cells Depositphotos Following a trail of evidence that started with a study of fruit flies nearly 25 years ago, researchers have found adding a hyperactive form of the protein Rac2 to macrophages, immune cells that eat pathogens, causes...
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Can you really be allergic to alcohol?
by Samuel J. White and Philippe B. Wilson, The Conversation Credit: Darlene Alderson from Pexels Some people get allergy-like symptoms when drinking alcohol, but can you really be allergic to alcohol? Alcohol allergies are rare, with documented cases primarily involving a rash. However, what often perplexes people are the symptoms that mimic allergies, such as wheezing,...
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Neutrophil-to-lymphocyte ratio can distinguish cystitis from OAB
by Elana Gotkine Serum neutrophil-to-lymphocyte ratio (NLR) can help differentiate interstitial cystitis/bladder pain syndrome (IC/BPS) from overactive bladder (OAB), according to a study published online Nov. 8 in BMC Urology. Hanwei Ke, from Peking University People’s Hospital in Beijing, and colleagues conducted a retrospective analysis involving 70 women diagnosed with IC/BPS, 20 diagnosed with OAB,...
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Researchers identify why cancer immunotherapy can cause colitis
Studies in mice reveal the mechanism that induces this severe side effect and point to a solution that kills the cancer without causing gastrointestinal issues AuthorNicole Fawcett Jacob Dwyer, Michigan MedicineResearchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment. They also...
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Major Study Identifies 15 Factors Linked to Early Dementia Risk
ByDAVID NIELDFading brain (Naeblys/iStock/Getty Images Plus)While dementia is much more common in older adults, hundreds of thousands of people are diagnosed with young-onset dementia (YOD) each year – and an extensive new study sheds some considerable new light on why. Most previous research in this area has looked at genetics passed down through generations, but...