by Zhang Nannan, Chinese Academy of Sciences SARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao’s groupIn the past four years, the pathogen responsible for Coronavirus Disease 2019 (COVID-19), SARS-CoV-2, has infected more than 770 million people and caused more than 6.9 million deaths worldwide. The severe impact of SARS-CoV-2 is often attributed to...
by Baker Heart & Diabetes Institute Pharmacological inhibition of EZH2 catalyzes pancreatic progenitor activation and β-cell maturation. The schematic outlines the progression from pancreatic multipotent progenitors to mature insulin-secreting β-cells, highlighting the regulatory target of EZH2 inhibitors, GSK126 and Tazemetostat. Credit: Signal Transduction and Targeted Therapy (2024). DOI: 10.1038/s41392-023-01707-xResearchers are zeroing in on the ultimate...
by American College of Physicians Credit: CC0 Public DomainPhysicians should be aware of a potential serious adverse effect associated with sotatercept use. A case report detailing serious and recurrent gastrointestinal bleeding is published in Annals of Internal Medicine. Sotatercept is an investigational medicine that has shown positive results for treating adults with pulmonary arterial hypertension. In...
by American College of Physicians Credit: Pixabay/CC0 Public DomainA new protein risk score developed to predict the risk of death for persons with heart failure (HF) has demonstrated good calibration and may help clinicians better stratify mortality risk in these patients. The score is published in Annals of Internal Medicine. Heart failure is a complex clinical...
Peer-Reviewed Publication UNIVERSITY OF VIRGINIA HEALTH SYSTEM RESEARCHER JOHN KIM, MD, IS A PULMONARY AND CRITICAL CARE EXPERT AT UVA HEALTH AND THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE.CREDIT: UVA HEALTH Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need...
Peer-Reviewed Publication BAYLOR COLLEGE OF MEDICINE Just like a doctor adjusts the dose of a medication to the patient’s needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window. Staying within the therapeutic window is important...
Artificial intelligence, coupled with data from an iPad coloring game, could assist in early diagnosis of autism, a new USC study shows. “These results indicate potential for an easy and novel method for early detection of autism and development coordination disorder,” said senior author Lisa Aziz-Zadeh, a professor at the USC Mrs. T.H. Chan Division...
AI can analyse X-rays and diagnose medical issues just as, or more, accurately than doctors, a new study led by the University of Warwick has found.X-ray analysis – illustrative artistic rendering. The AI, which has been trained on 2.8 million historic chest X-rays from over 1.5 million patients, scans X-Rays for 37 possible conditions. It...
Osaka UniversityJust as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell, for example, mitochondria power the cell and lysosomes keep the cell tidy. Although damage to these two organelles has been linked to aging, cellular...
Henswear envisions a transformative approach to health monitoring through nanomaterial-based sensors seamlessly integrated into everyday clothing.A team of engineers from the University of Delaware introduces wearable nanotechnology designed to accelerate recovery, with the added benefit of adaptability to existing fabrics. NEXT-GENERATION WEARABLE TECHNOLOGIES (Photo : University of Delaware)Thanks to new funding from NSF, Thostenson (pictured)...
