Liam Davenport DISCLOSURES Exposure to endocrine-disrupting chemicals (EDCs) via daily use of plastics is a major contributor to the overall disease burden in the United States and the associated costs to society amount to more than 1% of the gross domestic product, revealed a large-scale analysis. The research, published in the Journal of the Endocrine...
Year: <span>2024</span>
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‘Fake Xanax’ Tied to Seizures, Coma; Naloxone Ineffective
Bromazolam, a street drug that has been detected with increasing frequency in the United States, has reportedly caused protracted seizures, myocardial injury, comas, and multiday intensive care stays in three individuals, new data from the US Centers for Disease Control and Prevention (CDC) showed. The substance is one of at least a dozen designer benzodiazepines,...
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Delayed Meals Tied to Increased CVD Risk
TOPLINE:Beyond the nutritional quality of a diet, the timing of meals is important, with later first and last meals of the day associated with increased risks for cardiovascular diseases (CVDs), especially in women, results of a large prospective study suggested. METHODOLOGY:The study included 103,389 participants, mean baseline age 42.6 years and 79% women, who were...
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Tapering of inhaled steroids feasible for asthma controlled with benralizumab
by Elana Gotkine For patients with severe eosinophilic asthma controlled on bevacizumab, tapering of inhaled corticosteroids (ICS) is feasible and is not associated with worse asthma control, according to a study published online on Dec. 7 in The Lancet. David J. Jackson, M.P.H., from King’s College London, and colleagues conducted a phase 4 study involving...
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SGLT2 Inhibitors Begin to Show Therapeutic Potential in Rheumatology
Over just a decade, sodium-glucose cotransporter-2 (SGLT2) inhibitors have revolutionized the second-line treatment of type 2 diabetes by improving the control of blood sugar, and they’re also being used to treat heart failure and chronic kidney disease. Now, there’s growing evidence that the medications have the potential to play a role in the treatment of...
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Mental illness in patients with chronic kidney disease
by Karolinska Institutet Credit: Unsplash/CC0 Public DomainChronic kidney disease (CKD) affects more than 10% of adults worldwide. Mental health is an important yet under-recognized issue in patients with CKD. Depression is common and related to poor prognosis in CKD patients, but previous research has primarily focused on dialysis patients, leading to an insufficient understanding of depression...
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Study provides insights into depression via ophthalmology
by Anke Schlee, Max Planck Society A high-speed camera provides information on pupil size. Credit: Martin Otter MPI PsychiatryScientists from the Max Planck Institute of Psychiatry measured the pupillary reaction of participants while they were solving a task. In healthy participants, the pupils dilated during the task in anticipation of a reward, but this reaction was...
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Smartphone app could help prevent falls in older adults
by Binghamton University Weekly workout programs and example exercise instruction set with images as displayed to participants in the smartphone-based intervention group. Credit: Sensors (2023). DOI: 10.3390/s23177451Researchers at Binghamton University, State University of New York’s Motion Analysis Research Laboratory have developed an app to help study and prevent falls in older adults. Their research is published...
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A novel approach for lymph node metastasis treatment
by Tohoku University Osmotic pressure-and-viscosity-modified Docetaxel via lymphatic drug delivery system (LDDS) can inhibit tumor growth in the lymphatic system and prevent distant metastasis. Increases in osmotic pressure and viscosity lead to significant tumor inhibition in the sentinel lymph node (LN) and its’ downstream LN. Moreover, we found the underlying mechanism of increased osmotic pressure and...
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Is This the Cure for Restless Legs?
George Lundberg, MDDISCLOSURES I don’t rightly remember when I first learned of restless legs syndrome (RLS). It was many decades ago, and I recognized that once in a while, I would be restless during sleep, tossing and turning, seeking a favorable sleeping position. I felt like I just needed to move my legs around; my...