by Karolinska Institutet AI model ROC curve and human examiner performance. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-024-03329-4 A new international study led by researchers at Karolinska Institutet in Sweden shows that AI-based models can outperform human experts at identifying ovarian cancer in ultrasound images. The study is published in Nature Medicine. “Ovarian tumors are common and are often detected by chance,”...
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Yale study identifies molecular mechanism behind some lissencephaly disorders
Reviewed Yale UniversityJan 2 2025 Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders are often associated with seizures and intellectual disability and currently there are no available treatments. A new Yale study, however, has identified a molecular mechanism that underlies some lissencephaly disorders...
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THE WRONG SLEEP CYCLE CAN SERIOUSLY AFFECT YOUR MOOD
DECEMBER 30TH, 2024POSTED BY U. MICHIGAN (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY UNIVERSITY OF MICHIGAN A new study shows that when people’s sleep cycles aren’t aligned with their internal clocks, or circadian rhythms, it can have drastic effects on their moods. Conversely, however,...
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Advances in gene and cellular therapeutic approaches for Huntington’s disease
Peer-Reviewed Publication Higher Education Press image: Highlighting current and emerging gene and cell therapy strategies for Huntington’s Disease is crucial due to the disorder’s complexities and devastating impact. Looking ahead, a synergistic approach that integrates various cell types, genetic correction, and enhancement of the cerebral microenvironment offers significant potential for advancing therapeutic efficacy for Huntington’s...
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NIH officials assess threat of H5N1
Balancing enhanced vigilance and “business as usual”Peer-Reviewed Publication NIH/National Institute of Allergy and Infectious Diseases image: Photo of a wild bird. To the right is a colorized transmission electron micrograph of H5N1 virus particles (purple). H5N1 bird flu is widespread in wild birds worldwide, and in 2024 is causing a multistate outbreak in poultry and...
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Targeting tristetraprolin in basophils: A breakthrough in allergic inflammation treatment
Exploring the role of Tristetraprolin in basophil-mediated immune responses and its therapeutic potentialPeer-Reviewed Publication Institute of Science Tokyo image: TTP regulates inflammatory responses in basophils and isa promising therapeutic target for allergies.view more Credit: Science Tokyo Inflammation is a crucial part of the body’s defense mechanism, playing a key role in fighting infections and repairing tissue...
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New insights into protein roles in Duchenne muscular dystrophy
by CU Anschutz Medical Campus Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.108002 A new study has shed light on the complex interactions between dystrophin, a protein critical to muscle stability, and its partner protein, dystrobrevin, offering new pathways for understanding and treating Duchenne Muscular Dystrophy (DMD). Published in the December issue of the Journal of Biological Chemistry, researchers characterize...
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Mitochondrial DNA plays an underappreciated role in leukemia development
by St. Jude Children’s Research Hospital Xiujie Li-Harms, Ph.D. (pictured), director of laboratory operations in the lab of Mondira Kundu, MD, Ph.D., St. Jude Department of Cell & Molecular Biology, and first author on research published in Science Advances demonstrating the impact of mitochondrial DNA mutational burden on leukemogenesis, revealing a mutational “sweet spot” where leukemia development was...
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Active lifestyle significantly lowers risk of 19 chronic diseases, study finds
by University of Iowa Credit: Unsplash/CC0 Public Domain University of Iowa researchers are recommending all patients be surveyed about their physical activity levels, after a new study underscores the link between physical activity and chronic disease. The study, led by Lucas Carr, associate professor in the Department of Health and Human Physiology, examined responses from more...
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Norovirus: What to know and how to avoid it
by Deb Balzer, Mayo Clinic Cluster of norovirus virions. Credit: CDC If you’ve been bit by a stomach bug lately, you’re not alone. Noroviruses are usually more widespread in the fall and winter, but you can get sick from the virus any time of the year. The Centers for Disease Control and Prevention (CDC) says norovirus...