by Juntendo University Research Promotion Center Researchers have found that stress decreases the capacity of specialized cells called programmed death ligand 2-positive macrophages to clear out dead cells in lesion sites, leading to worsening of skin allergies. Credit: Soichiro Yoshikawa / Juntendo University, Japan Psychological stress is known to exacerbate skin allergies, but the underlying...
Retatrutide Produces Greatest Weight Loss
Alicia Ault January 07, 2025 2388 Added to Email Alert A systematic review of 26 randomized controlled trials (RCTs) finds that among glucagon-like peptide 1 (GLP-1) receptor agonists and co-agonists on the market or still being investigated, the experimental drug retatrutide (Eli Lilly and Company) produces the greatest weight loss. The review, conducted by researchers...
Sedentary work and irregular hours significantly impact sleep health, study shows
by John Dudley, University of South Florida Credit: CC0 Public Domain People whose jobs are highly sedentary—an estimated 80% of the modern workforce— experience a much higher risk of insomnia symptoms, according to a new study led by University of South Florida psychologist Claire Smith. The findings, newly published in the Journal of Occupational Health Psychology, show that among...
Significantly shorter treatment regimens for tuberculosis in children and adults now recommended
by American Thoracic Society Credit: Unsplash/CC0 Public Domain Tuberculosis remains a public health crisis. The World Health Organization’s Global Tuberculosis Report released in November 2024 painted a sobering picture; approximately 8.2 million people were newly diagnosed with TB in 2023, the highest number since the organization began global TB monitoring in 1995. A major challenge in tuberculosis treatment...
Study shows head trauma may activate latent viruses, leading to neurodegeneration
by Tufts University Players injured in sports like soccer, boxing, football, and soldiers exposed to concussive forces and experiencing head trauma are at increased risk of neurodegenerative conditions over time. Credit: Ardfern Concussions and repetitive head trauma in sports like football and boxing, once accepted as an unpleasant consequence of intense athletic competition, are now recognized...
New evidence links dementia to problems with the brain’s waste clearance system
by Zara Abrams, Keck School of Medicine of USC Cross-sectional association between the diffusion analysis along PVS (ALPS) index and the validated UDS3-EF in MarkVCID cohort (A), UCD_ADRC cohort (B), UCSF_MAC cohort (C), and FHS cohort (D). Credit: Alzheimer’s & Dementia (2024). DOI: 10.1002/alz.14453 A study from the Keck School of Medicine of USC has tested a biomarker...
New family of protein-based antagonists shows promise against leukemia
by Beatriz Lucas, Max Planck Society Credit: Dr. Kateryna Maksymenko/ Max Planck Institute for Biology Tübingen, Germany In a significant advancement for cancer research, a team of scientists from Max Planck Institute for Biology Tübingen, University Hospital Tübingen, and Osnabrück University successfully designed a new family of protein-based antagonists that selectively block the G-CSFR receptor, which...
Study reveals neutrophils’ dynamic role in cancer progression
Reviewed Chinese Academy of SciencesJan 7 2025 Neutrophils are the most abundant white blood cells in the human body, primarily recognized for their essential roles in fighting infections and regulating inflammation. However, their involvement in cancer progression has long been a subject of intrigue and confusion. These immune cells exhibit a paradoxical behavior within tumors, where...
Decades of research push cytomegalovirus vaccine closer to reality
By Dr. Chinta SidharthanReviewed by Susha Cheriyedath, M.Sc.Jan 6 2025 With decades of research culminating in innovative vaccine candidates, scientists are closer than ever to combating a virus that causes birth defects and transplant complications worldwide. Research: A vaccine against cytomegalovirus: how close are we? Image Credit: Kateryna Kon / Shutterstock In a recent review published in The Journal of Clinical Investigation,...
SCIENCE & TECHNOLOGY NEWS
Tinkering with the “clockwork” mechanisms of life Posted Today Living organisms monitor time—and react to it—in many different ways, from detecting light and sound in microseconds to responding physiologically in pre-programmed ways via their daily sleep cycle, monthly menstrual cycle, or changes in the seasons. The research team led by Prof. Alexis Vallée-BélisleThe has discovered how...