January 3, 2025 01:08 PM ESTUpdated 02:13 PM PharmaLawHealth TechEli Lilly seeks to join lawsuit over end of tirzepatide shortageShelby LivingstonSenior health tech reporterEli Lilly has asked to intervene in litigation between a compounding pharmacy trade group and the FDA over the agency’s decision to remove Lilly’s blockbuster obesity and diabetes drug tirzepatide from its...
Year: <span>2025</span>
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Intestinal ultrasound feasible for detecting pediatric inflammatory bowel disease
by Lori Solomon Intestinal ultrasound (IU) can be considered a screening tool for pediatric inflammatory bowel disease (IBD), according to a study published online Dec. 24 in the Journal of Pediatric Gastroenterology and Nutrition. Hamza Hassan Khan, M.D., from the Medical University of South Carolina in Charleston, and colleagues compared IU findings to clinical disease, fecal...
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How a simple amino acid could shape immune response
by University of Oxford Credit: Zhi Yi Wong A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response. Germinal center (GC) B cells are responsible for producing antibodies. The cells have some of the highest proliferation rates of all...
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Broken Sleep Linked to MASLD
Marilynn Larkin December 30, 2024 0322 TOPLINE: Fragmented sleep — that is, increased wakefulness and reduced sleep efficiency — is a sign of metabolic dysfunction—associated steatotic liver disease (MASLD), a study using actigraphy showed. METHODOLOGY: TAKEAWAY: IN PRACTICE: “We concluded from our data that sleep fragmentation plays a role in the pathogenesis of human MASLD....
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How chronic illness affects families—and how to cope when you know your loved one is going to die
by John Frederick Wilson, The Conversation Credit: CC0 Public Domain Living with a chronic illness in the family is hard. It’s even harder if you know that the person you love will get worse and won’t recover from their condition. Sadly, it can happen to any family at any time. Anyone—a grandparent, parent, sibling or partner—can...
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Clinical manifestations differ between interstitial cystitis, bladder pain syndrome
by Lori Solomon Interstitial cystitis and bladder pain syndrome (IC/BPS) vary in clinical manifestation, according to a study published online Oct. 18 in the International Journal of Urology. Aya Niimi, M.D., Ph.D., from the University of Tokyo, and colleagues used patient registry data to describe clinical manifestations of patients with IC and BPS. The analysis included data from...
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Tinnitus risk increased for patients with gastroesophageal reflux disease
by Elana Gotkine Patients with gastroesophageal reflux disease (GERD) have an increased risk for tinnitus, according to a study published online Dec. 3 in Scientific Reports. Noting that acid reflux may disrupt the homeostasis of the middle and inner ear through the Eustachian tube, Sung-Woo Kang, from the Kyung Hee University College of Korean Medicine in Seoul, and colleagues explored...
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Prevalence of dementia diagnoses increased in individuals with autism diagnosis
by Elana Gotkine Individuals with an autism spectrum disorder (ASD) diagnosis have an increased prevalence of identified dementia diagnoses, according to a research letter published online Jan. 2 in JAMA Network Open. Giacomo Vivanti, Ph.D., from the A.J. Drexel Autism Institute at Drexel University in Philadelphia, and colleagues conducted a retrospective cohort study to examine the nationwide prevalence...
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Study compares single-inhaler triple therapies for treatment of COPD
by Elana Gotkine For patients with chronic obstructive pulmonary disease (COPD), budesonide-glycopyrrolate-formoterol does not improve clinical outcomes compared with fluticasone-umeclidinium-vilanterol, according to a study published online Dec. 30 in The BMJ. William B. Feldman, M.D., M.P.H., from Brigham and Women’s Hospital in Boston, and colleagues compared the effectiveness and safety of budesonide-glycopyrrolate-formoterol, a twice-daily metered dose inhaler,...
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Study shows ‘good’ cholesterol may protect against brain atrophy, dementia
by UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report. The findings, published in the Journal of Clinical Medicine, could give doctors and patients more insight into factors that affect cognitive health in aging...