By American Association for the Advancement of ScienceJanuary 1, 20253 Comments3 Mins Read FacebookTwitterPinterestTelegram Share Researchers uncovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) linking neuronal activity to mitochondrial DNA transcription, crucial for maintaining brain function. Enhancing E-TCmito in aged mice improved cognition, offering a potential therapeutic target for age-related cognitive decline and neurodegenerative diseases....
Year: <span>2025</span>
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Why sugar cravings persist after the holidays—and how to beat them
by Cynthia McCormick Hibbert, Northeastern University Credit: Pixabay/CC0 Public Domain You’ve put away the candy canes, swept up the cookie crumbs and have vowed not to finish the box of specialty chocolates you received. But if you’re like many people who have indulged—or overindulged—in confectionary treats during the holidays, you may find winding down your sugar consumption to...
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Newly identified Type R capillaries crucial for bone remodeling and aging
by Max Planck Society Coupling of type R capillaries and remodeling bone: Distribution of EMCN+ VEGFR3- Type R capillaries (red) around trabecular bone marked by Sp7-mCherry+ osteoblasts (yellow). Credit: MPI for Molecular Biomedicine / Vishal Mohanakrishnan Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses. Bone dynamics...
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Why some people’s hair and nails grow quicker than others
by Michelle Moscova, The Conversation Credit: Unsplash/CC0 Public Domain Throughout recorded history, our hair and nails have played an important role in signifying who we are and our social status. You could say they separate the caveman from the businessman. ADVERTISING It was no surprise then that many of us found a new level of appreciation for...
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Y chromosome’s unexpected impact on aging and disease in men
By Priyanjana Pramanik, MSc.Reviewed by Susha Cheriyedath, M.Sc.Jan 5 2025 Why losing the Y chromosome is more than genetics—it’s a key to understanding male health disparities. Review Article: The effects of loss of Y chromosome on male health. Image Credit: Rost9 / Shutterstock In a recent review article in the journal Nature Reviews Genetics, researchers discussed the current understanding regarding the...
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Could you have hypothyroidism?
by Mayo Clinic News Network Credit: Pixabay/CC0 Public Domain You’ve been feeling fatigued and have gained some weight. It could be just a sign that you’re getting older, but there might be a chance these general symptoms are caused by hypothyroidism. Dr. Victor Bernet, a Mayo Clinic endocrinologist, says a blood test can confirm the...
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Impact of exosomal and cell-free circRNAs on cancer drug resistance
Peer-Reviewed Publication ELSP The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle through the blood circulation as cell-free molecules or in exosomes, small vesicles where they are transported to various cells. Published in ExRNA, the...
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Aging changes some brain cells more than others
By Paul McClure January 02, 2025 Certain brain cells respond to aging differently than others DALL-E View 3 Images View gallery – 3 images Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more...
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Scientists Discover Common Virus Could Be Causing a Type of Alzheimer’s
Health06 January 2025 ByJess Cockerill CMV-infected human placental cell. (Nephron/CC BY-SA 3.0/Wikimedia Commons) Researchers have discovered a link between a chronic gut infection caused by a common virus and the development of Alzheimer’s disease in some people. Most people encounter cytomegalovirus (CMV) during childhood, and after the initial infection the virus remains in the body for life, usually dormant. By the age of...
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Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
By Helmholtz Zentrum MünchenJanuary 6, 20251 Comment5 Mins Read FacebookTwitterPinterestTelegram Share A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein. Credit: SciTechDaily.com Researchers have discovered that...