JUNE 25, 2024
by Cesareo Contreras, Northeastern University
Microscopy images demonstrating the four classes in the BACH dataset. Credit: Cancers (2024). DOI: 10.3390/cancers16122222
Earlier this year, Northeastern University researchers unveiled a web-based artificial intelligence tool designed to diagnose prostate cancer at a faster and more accurate rate.
Now, the same group, led by bioengineering professor Saeed Amal, has developed a new AI architecture designed to detect breast cancer that the researchers say has achieved an accuracy rate of 99.72%.
Breast cancer accounts for 30% of new female cancer cases each year, and in 2024, an estimated 42,500 women will die from it, according to the American Cancer Society.
Research on the findings was published in the journal Cancers.
These projects are part of a larger effort by Amal to create an online framework doctors can access to diagnose a range of cancers using these innovative AI technologies. Amal says the new tool will “redefine digital pathology.”
He and his team recently submitted an invention disclosure with the Center for Research Innovation on the idea.
“The AI would look at the high-resolution images and would learn from historical data how to identify cancer patterns and perform diagnoses,” he says. “The AI can’t miss a tumor in the biopsy and won’t be exhausted after diagnosing 10 or 20 people.”
Ideally, this framework will enable doctors to not only treat patients more quickly and accurately, but also help with the development of new AI models that can be used to diagnose rare and uncommon cancers that lack a lot of patient data,” he says.
For the breast cancer project, researchers took advantage of publicly available datasets containing images of malignant and benign breast tissue found on the Breast Cancer Histopathological Database.
With this data on hand, the team built an ensemble deep learning model that utilized various models for increasing the accuracy and reduction of the error and trained them on the breast tissue image data, Amal says.
“It’s like taking the diagnosis of multiple doctors and vote to pick the best decision,” he says.
More information: Aadhi Aadhavan Balasubramanian et al, Ensemble Deep Learning-Based Image Classification for Breast Cancer Subtype and Invasiveness Diagnosis from Whole Slide Image Histopathology, Cancers (2024). DOI: 10.3390/cancers16122222
Journal information: Cancers
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