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Ketamine carries risks, say researchers. Yet for some patients, it’s ‘the only thing that works’

by Liz Mineo, Harvard Gazette Credit: Unsplash/CC0 Public Domain Ketamine carries risks, say researchers. Yet for some patients, it’s “the only thing that works.” At the Ketamine Clinic for Depression at Massachusetts General Hospital, patients make their way each day to receive intravenous infusions of the powerful anesthetic that has become an alternative therapy for...

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Regulator recommends two devices to reduce the severity of tics in people with Tourette syndrome

by Jane Icke, University of Nottingham Credit: University of Nottingham Two technologies that are based on research by University of Nottingham experts to reduce the severity of tics in people with Tourette syndrome (TS) are closer to patient use after being recommended in draft guidance by NICE. The two technologies are being developed utilizing research and...

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Students develop AI model for middle ear disease detection

by Bernice Chan, University of Southern California Credit: Pixabay/CC0 Public Domain Understanding the middle ear is essential—not only for hearing but also for balance and quality of life. According to the National Institutes of Health, in the U.S., one in eight adults has hearing loss, and nearly 28% of those with moderate to severe loss face...

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Algorithm can identify subtle changes in a person’s voice for early Parkinson’s detection

by University of South Australia Credit: Unsplash/CC0 Public Domain Algorithms that can detect subtle changes in a person’s voice are emerging as a potential new diagnostic tool for Parkinson’s disease, according to researchers from Iraq and Australia. Speech impairments are often the first indicators of the fastest-growing neurological disease in the world, affecting more than 8.5...

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New genetic explanation for heart condition revealed

by University College London Credit: Pixabay/CC0 Public Domain A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single “aberrant” genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College...

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Changing Concepts in Hyperthyroidism Management

Darcy Lewis November 07, 2024 3218 CHICAGO — Endocrinologists may be shifting toward greater use of antithyroid drugs (ATDs) over radioactive iodine (RAI) for initial treatment of Graves’ disease. Severe thyrotoxicosis remains rare but is challenging to treat. And investigational agents like batoclimab and K1-70 hold promise for the future of hyperthyroidism management. These are...

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Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency, study reveals

by University of Vienna Chemical imaging of active gut microbes. After brief incubation with heavy water, culture medium and a drug, various chemical bonds (here C–D and C–H) in the stool sample are shown in yellow and green, their ratio in yellow-purple (left). Selected microbes are detected in the same image section with fluorescence-labelled oligonucleotide...

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AI enhances early detection of pancreatic cysts

by Ohio State University Medical Center Using tiny cameras, Somashekar Krishna, MD, and his team at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute are able to explore a patient’s pancreas with a “virtual biopsy” that gives them a microscopic view of the cyst wall. They then...

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Protein disruption reveals potential treatment option for people with debilitating skin condition

by Micah Hardge, University of Alabama at Birmingham Neutrophils and macrophages in HS skin. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2409274121 Hidradenitis suppurativa, commonly referred to as HS, is a debilitating skin condition that causes chronic inflammation on the surface of the skin. This condition is characterized by painful bumps or boils that form...

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Predicting the risk of requiring long-term care based on three physical performance tests

by University of Tsukuba Credit: Mikhail Nilov from Pexels Health centers across Japan conduct simple physical performance tests for older adults, including the single-leg balance and sit-to-stand tests. Based on a follow-up study of approximately 1,000 individuals, researchers at University of Tsukuba have developed an evaluation scale that uses the combined scores of three simple physical...