by Kyushu University HGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitration sites of HGF and blocks nitration. The team hopes that this can eventually lead to therapies that can treat age-related muscle atrophy and impaired muscle regeneration. Credit:...
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Public humiliation is still a common teaching tool in medical education—here’s how it leaves patients worse off
by Carolyn Heward, Luisa Wigg and Wendy Li, The Conversation Credit: Unsplash/CC0 Public Domain Imagine being questioned about complex technical knowledge in front of your peers, supervisors, and members of the public—knowing that a wrong answer could lead to public ridicule. This is the reality for many medical students, with up to 90% of medical students experiencing public humiliation...
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Colchicine no benefit for painful knee osteoarthritis
by Lori Solomon Colchicine fails to improve knee pain, function, or size of synovial effusions with painful knee osteoarthritis (OA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in Washington, D.C. Jonathan Samuels, M.D., from NYU Langone in Rye Brook, New York, and...
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Now carrots too? Expert discusses why there have been so many food recalls lately
by Erin Kayata, Northeastern University Credit: Unsplash/CC0 Public Domain It seems like every day there is a new food recall. This time, it’s carrots. Multiple brands of the vegetable sold across 18 states have been recalled due to possible E.coli contamination, according to the Centers for Disease Control and Prevention. The 39 cases were reported across 18 states, resulting...
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AI advice influences radiologist and physician diagnostic decisions incorrectly, according to new study
by Radiological Society of North America Chest radiograph (CXR) examples of (A, C) local (feature-based) AI explanations and (B, D) global (prototype-based) AI explanations from a simulated AI tool, ChestAId, presented to physicians in the study. In all examples, the correct diagnostic impression for the radiograph case in question is “right upper lobe pneumonia,” and the...
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Lifestyle and risk factor changes improved AFib symptoms, not burden, over standard care
by American Heart Association A 12 lead ECG showing atrial fibrillation at approximately 150 beats per minute. Credit: James Heilman, MD/Wikipedia/CC BY-SA 3.0 Treatment with the Type 2 diabetes medication metformin, lifestyle changes, or a combination of both did not improve atrial fibrillation (AFib) burden or progression when compared with standard care, according to preliminary late-breaking...
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PNA5 protein shows potential for treating Parkinson’s-related cognitive decline and dementia
by University of Arizona PNA5 blunts neuronal cell loss in the hippocampus. Credit: Experimental Neurology (2024). DOI: 10.1016/j.expneurol.2024.114926 A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson’s...
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Study: Eating more than 45% of calorie intake after 5 p.m. alters glucose levels, with serious consequences for health
by Teresa Bau and Sònia Armengou, Open University of Catalonia Credit: Nutrition & Diabetes (2024). DOI: 10.1038/s41387-024-00347-6 Although people have always said that having a light and early dinner is better, a study by the Universitat Oberta de Catalunya (UOC) and Columbia University has provided the scientific grounds for this argument. According to a study published in Nutrition & Diabetes, consuming...
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Landmark study reveals over 100,000 American youth living with inflammatory bowel disease
Comprehensive analysis reveals U.S. pediatric IBD rates increased, ranking among highest globallyPeer-Reviewed Publication Crohn’s & Colitis Foundation of America Embargoed until Wednesday, Nov. 20 @ 9AM ET New York, NY – November 20, 2024 – A groundbreaking study published today in Gastroenterology provides the most comprehensive assessment to date of pediatric inflammatory bowel disease (IBD) prevalence in...
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Trial shows alcohol-mimicking medication can give laryngeal dystonia patients back their voice
Sodium oxybate is the first oral treatment for laryngeal dystonia to show efficacy at providing temporary relief for debilitating symptoms that impact speaking, according to the results of a Mass Eye and Ear-led clinical trialPeer-Reviewed Publication Mass Eye and Ear image: Clinical treal lead author Kristina Simonyan, MD, PhD, Dr med, vice chair for clinical research...