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Fat cells have epigenetics-based memory: Researchers discover mechanism behind weight loss yo-yo effect

by Fabio Bergamin, ETH Zurich Human AT retains cellular transcriptional changes after BaS-induced WL. Credit: Nature (2024). DOI: 10.1038/s41586-024-08165-7 Anyone who has ever tried to get rid of a few extra kilos knows the frustration: the weight drops initially, only to be back within a matter of weeks—the yo-yo effect has struck. Researchers at ETH Zurich have now...

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New therapies offer effective treatment for managing Tourette syndrome

by Kennedy Krieger Institute Credit: Pixabay/CC0 Public Domain Researchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Their recent publication highlights how behavioral therapies—an approach that teaches patients how to manage certain tics using behavioral strategies—are proving to be the most effective treatment. The findings are published in the...

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Surprising connection between COVID-19 and cancer regression

by Northwestern University Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI179527 A new study led by scientists from the Northwestern Medicine Canning Thoracic Institute and published in the Journal of Clinical Investigation has revealed a connection between COVID-19 infection and cancer regression. The team’s discovery could pave the way for novel cancer treatments. In an unexpected twist, the scientists observed that the...

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Doctors may soon use an AI-driven solution to personalize antibiotic prescriptions

by SingHealth Credit: Unsplash/CC0 Public Domain Doctors may soon use an AI-driven solution to swiftly prescribe a personalized antibiotic regimen for patients with just a few mouse clicks instead of giving general treatment. The antibiotic regimen can then be adjusted, if necessary, when bacterial culture and other investigation test results become available. Known as the Augmented...

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Transcranial direct current stimulation found to be safe, effective for tardive dyskinesia

by Lori Solomon Transcranial direct current stimulation (tDCS) may be an effective and safe treatment for improving the facial-oral motor symptoms of tardive dyskinesia (TD) in chronically hospitalized patients with schizophrenia, according to a study published online in the October issue of Clinical Neurophysiology. Xiaoli Lyu, from the Teaching Hospital of Yangzhou University in China, and colleagues evaluated...

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Cardiovascular drugs may reduce dementia risk

by Karolinska Institutet Credit: Unsplash/CC0 Public Domain Common cardiovascular drugs are linked to a lower risk of dementia in older age, according to a new study from Karolinska Institute, published in Alzheimer’s & Dementia. Cardiovascular disease and dementia are major public health challenges that cause a significant burden on both health care and society. A new study from Karolinska Institutet in...

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Smarter blood tests could deliver faster diagnoses and improved outcomes

by Dalin Clark, Michigan State University Small molecule modulation of protein corona significantly enhances deep plasma proteome profiling. Credit: Mahmoudi Group Medical professionals have long known that the earlier a disease is detected, the higher the chance for a better patient outcome. Now, a multidisciplinary team of Michigan State University researchers, in collaboration with experts from...

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GERD linked to cardiovascular risk factors: New insights from Mendelian randomization study

Peer-Reviewed Publication Tsinghua University Press image:  This graphic show mediation MR analysis to investigate how LDL cholesterol, HDL cholesterol, and hypertension mediate the effect of GERD on myocardial infarction.view more  Credit: Wu Qiang, Chinese PLA General Hospital, China; Su Qiang, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, China A recent study published in the Journal of Translational...

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New Clinical Study Confirms the Anti-Obesity Effects of Kimchi

Regular Consumption Reduces Body Fat and Boosts Gut HealthPeer-Reviewed Publication National Research Council of Science & Technology image:  Diagrammatic representation of the results of the clinical trial on the anti-obesity effects of kimchiview more  Credit: World Institute of Kimchi (WiKim) Approximately 16% of the global population, or about 890 million people, suffer from obesity. The World...

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First American Gastroenterological Association living guideline for moderate-to-severe ulcerative colitis

Subhead: Patients should start advanced therapies early rather than gradual step-up treatmentPeer-Reviewed Publication American Gastroenterological Association Bethesda, MD (Nov. 15, 2024) — The American Gastroenterological Association (AGA) has released a new clinical guideline on the pharmacological management of moderate-to-severe ulcerative colitis, published today in Gastroenterology. This guideline groups the 12 currently available advanced treatments based on...