by University of Basel Post-hoc analysis of the drug effect on the primary outcome per cognitive baseline group, violin plots. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02820-1 Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like...
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Diabetes drug shows promise in protecting kidneys
by Osaka Metropolitan University More red areas in the kidney indicate higher oxygen levels. Credit: Osaka Metropolitan University Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention. An Osaka Metropolitan University-led research group has investigated how such drugs...
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New oral drug to calm abdominal pain
Researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractionsPeer-Reviewed Publication University of Queensland University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin...
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Why substitute sugar with maple syrup?
First human clinical trial explores how replacing refined sugars with pure maple syrup can help in preventing metabolic diseasePeer-Reviewed Publication Ellen LaNicca Fearless PR image: Dr. Andre Marette, PhD, was the lead scientist for first human trial substituting refined sugars with pure maple syrup. The study found significant improvement in multiple cardiometabolic risk factors. view more Credit: Maple...
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When hepatitis E viruses attack nerve cells
Peer-Reviewed Publication Ruhr-University Bochum image: Primary neurons from human kidney cells infected with Hepatitis E and excreted in the urineview more Credit: © Molekulare und Medizinische Virologie, RUB Hepatitis E is a common disease worldwide, but it often remains undetected. “There’s no precise data on how often the infection affects the neurological system,” says Michelle Jagst....
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Erase the trace: New frontiers in scar prevention and skin repair
Peer-Reviewed Publication ELSP image: Disruptions during wound healing phases (inflammation, proliferation, and remodeling) can result in scar formation. Higher levels of inflammatory markers (TGF-β1, TGF- β2, VEGF) and type 1 collagen are present in scars. Current treatments for scars include pressure garments, corticosteroids, laser therapy, and scar excision. Current research explores Yes-associated protein and harnesses...
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SCIENCE & TECHNOLOGY NEWS
Human sense of touch consists of 16 unique types of nerve cells Posted Yesterday No less than 16 different types of nerve cells have been identified by scientists in a new study on the human sense of touch. Comparisons between humans, mice and macaques show both similarities and significant differences. The study is a collaboration between...
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Spironolactone, a blood pressure medication, may help reduce risk of new heart failure
by American Heart Association Spironolactone 50 mg. Credit: Spirono/Wikimedia Commons, CC BY New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack. However, it did not significantly reduce the number of deaths or other severe heart-related events, according to...
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Staggeringly high’ discontinuation rates for GLP-1 drugs like Ozempic or Wegovy
by Kristin Samuelson, Northwestern University Credit: Markus Winkler from Pexels The use of diabetes and weight-loss medications like Ozempic or Wegovy—called GLP-1 drugs—has exploded in recent years, with 12% of U.S. adults having used one despite the high cost, according to a June 2024 poll. What’s less talked about is that 50%–75% of people who start taking these...
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What is Neuroinflammation?
By Syed S. A.Reviewed by Danielle Ellis, B.Sc. What is neuroinflammation?Causes of neuroinflammationThe impact of neuroinflammationPotential treatments and preventionReferences What is neuroinflammation? Neuroinflammation refers to an inflammatory reaction in the brain or spinal cord. It is driven by the production of molecules such as cytokines, chemokines, reactive oxygen species (ROS), and secondary messengers, which are released by...