by Drexel University In the study, 31 pediatric practices across three sites were randomly assigned to an experimental condition involving training and supervision in the universal, standardized, high-fidelity use of M-CHAT-R/F or to usual care. Credit: The A.J. Drexel Autism Institute New research from Drexel University’s A.J. Drexel Autism Institute found that the use of standardized...
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Protective genetic mutation offers new hope for understanding autism and brain development
by Genomic Press Credit: Human Brain Project Tel Aviv University researchers have made a discovery that could enhance our understanding of genetic mutations and their role in brain development. ADVERTISING The study, “Protective inherited mutations in activity-dependent neuroprotective protein (ADNP): the good, the bad, and the ugly,” published in Genomic Psychiatry, reveals that not all genetic mutations are...
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Neural circuits reveal new insights into how we navigate space and store memories
by Pat Harriman, University of California, Irvine Distinct RSC neuronal circuits corresponding to M2- and AD-projection neurons revealed by retrograde adeno-associated (rAAV2-retro) virus and anterograde AAV-SynaptoTAG2 virus. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02819-8 Researchers led by the University of California, Irvine are the first to reveal how two neural circuits located in the brain’s retrosplenial cortex are directly...
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Cholesterol may not be the only lipid involved in trans fat-driven cardiovascular disease
by Salk Institute Graphical abstract. Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.10.016 Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary...
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New lens system for endoscopes could allow physicians to see inside the body like never before
by Wayne Gillam, University of Washington – Department of Electrical & Computer Engineering An illustration of the endoscope lens system designed by UW ECE and Physics Professor Arka Majumdar and his research team. A coin-shaped metalens at the front end of the endoscope directs three cones of red, green, and blue light to a rainbow of...
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Research claims cannabis use can cause chromosomal damage, increasing cancer risk and harming offspring
by Society for the Study of Addiction Credit: Unsplash/CC0 Public Domain Cannabis use causes cellular damage that increases the risk of highly cancerous tumors, according to a paper published in Addiction Biology. The paper describes cannabis as a “genotoxic” substance because it damages a cell’s genetic information, which can lead to DNA mutations, accelerated aging, and cancer. ADVERTISING...
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Clinical trial shows positive results for potential treatment to combat a rare immune-mediated disease
by Mass General Brigham Credit: Pixabay/CC0 Public Domain An international, Phase III clinical trial led by investigators at Mass General Brigham could improve the treatment of a rare disease that can cause debilitating symptoms. The study, published in the New England Journal of Medicine, found that treatment with inebilizumab greatly reduced the symptoms of immunoglobulin G4–related disease...
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It’s my brain’s fault’: Why teenagers often make less than optimal decisions
by Public Library of Science Age-dependent decreases in sub-optimal and ‘noisy’ decisions associated with improved higher-level cognitive and planning skills. Created with Adobe Illustrator. Credit: Robert Wenzl / University Clinic Würzburg (CC-BY 4.0) Adults exhibit a general tendency to make better decisions than adolescents, and this improvement drives an increase in specific and more sophisticated choice...
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Measles cases surge 20%, global study shows
An electron micrograph of the measles virus. Credit: CDC/ Courtesy of Cynthia S. Goldsmith Measles infections soared by a fifth last year to over 10 million cases globally, revealing alarming gaps in vaccine coverage, a study showed Thursday. ADVERTISING Worldwide, there were an estimated 10.3 million measles cases in 2023, according to a joint publication by the...
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Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases
by University of Rochester Medical Center Credit: Pixabay/CC0 Public Domain Gene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there is a big problem: size. The genes that are dysfunctional in muscular dystrophies are often extremely large, and current delivery methods can’t courier such substantial genetic loads into the body....