by University of Helsinki Snapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna Rappe Mitochondria play an essential role in maintaining cellular health. When damaged, they are removed through a recycling process called mitophagy, which is crucial for the function of long-lived cells,...
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How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors
by Tel-Aviv University Graphical abstract. Credit: Neuron (2024). DOI: 10.1016/j.neuron.2024.10.014 Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor (NMDAR)—long studied primarily for its role in learning and memory—also plays a crucial role in stabilizing brain activity. By setting the “baseline” level for activity in neural networks, the NMDAR helps maintain stable brain function amidst...
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Study reveals COVID-19 vaccine safety in patients with atrial fibrillation/flutter
by Korea University College of Medicine Subgroup analyses revealed significantly higher risk of thrombo-embolic events in patients with atrial fibrillation/flutter (AF/AFL) not receiving oral anticoagulants (OACs). COVID-19 vaccination is relatively safe for patients with AF/AFL, especially with concurrent OACs. Credit: Professor Jin Oh Na from Korea University College of Medicine Development of the coronavirus disease...
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New evidence links gut microbiome to chronic disease outcomes
Peer-Reviewed Publication First Hospital of Jilin University image: Functions of the gut microbiome. Created with BioRender.com. SCFA, short chain fatty acids.view more Credit: By Connor Prosty, Khaled Katergi, Jesse Papenburg, et al. The gut microbiome, an ecosystem of trillions of microorganisms in the human digestive tract, has been increasingly linked to chronic diseases. Research led by...
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Zinc deficiency promotes Acinetobacter lung infection: study
Findings suggest anti-IL-13 antibodies as treatment to protect against bacterial pneumonia in patients with zinc deficiencyPeer-Reviewed Publication Vanderbilt University Medical Center Dietary zinc deficiency promotes lung infection by Acinetobacter baumannii bacteria — a leading cause of ventilator-associated pneumonia, according to a new study published Nov. 15 in the journal Nature Microbiology. A Vanderbilt University Medical Center-led...
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Selenium metabolism and selenoproteins function in brain and encephalopathy
Peer-Reviewed Publication Science China Press image: GPXs are responsible for reducing reactive oxygen species (ROS), such as hydrogen peroxide (H2O2) to water by using glutathione (GSH). TXNRDs not only reduce thioredoxin (Trd), but also non-disulfide substrates, such as hydroperoxides, by consuming NADPH. DIOs are mainly involved in regulating deiodination reactions, which converting T4 to T3...
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Scientists transform blood into regenerative materials, paving the way for personalized, blood-based, 3D-printed implants
Peer-Reviewed Publication University of Nottingham image: Researchers holding 3D printed PA-blood constructs.view more Credit: University of Nottingham Scientists have created a new ‘biocooperative’ material based on blood, which has shown to successfully repair bones, paving the way for personalised regenerative blood products that could be used as effective therapies to treat injury and disease. Researchers from...
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A sad girl
According to new research out of the Boston health system Mass General Brigham, the number of people with long Covid could be three times as high as previous studies have found. The researchers estimate nearly 23 percent of people have endured long-term symptoms, lasting at least two months, from a Covid-19 infection. That compares to a...
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How ulcerative colitis can affect the eyes
Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD). The underlying inflammation of UC can lead to eye conditions such as scleritis and uveitis. Without treatment, some conditions may lead to vision loss. UC is a chronic condition that primarily affects the large intestine. It is a type of IBD, meaning that inflammation...
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What is the 333 rule for anxiety?
The 333 rule may ease anxiety by shifting a person‘s attention back to the present moment, a technique known as grounding. To use the rule, people can identify 3 objects they can see, hear, and touch or move. An advantage of the 333 rule is that it does not require any supplies, such as a...