by Justin Jackson , Medical Xpress Credit: Pixabay/CC0 Public Domain Researchers at Leiden University Medical Center and Radboud University Medical Center in the Netherlands have demonstrated promising safety and efficacy of a late-liver-stage attenuated malaria parasite vaccine in a small clinical trial. The study found that immunization with a genetically modified Plasmodium falciparum parasite, known...
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UnitedHealth moves money ‘from their right pocket to their left’
UnitedHealth Group is paying many of its own physician practices significantly more than it pays other doctor groups in the same markets for similar services, STAT reporters reveal in Part 5 of the series Health Care’s Colossus. For some types of care, the company’s insurance subsidiary doles out twice the average market price at its own...
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Machine learning and supercomputer simulations predict interactions between gold nanoparticles and blood proteins
by University of Jyväskylä The cover image of 10/2024 issue of Bioconjugate Chemistry, displaying a tunable ligand-protected gold nanocluster as a drug delivery system with high affinity to integrin αvβ3, a key regulator of adhesion and signaling in various biological processes that plays a critical role in cancer progression. Credit: María Francisca Matus from University of Jyväskylä....
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Study: Eating more than 45% of calorie intake after 5 p.m. alters glucose levels, with serious consequences for health
by Teresa Bau and Sònia Armengou, Open University of Catalonia Credit: Nutrition & Diabetes (2024). DOI: 10.1038/s41387-024-00347-6 Although people have always said that having a light and early dinner is better, a study by the Universitat Oberta de Catalunya (UOC) and Columbia University has provided the scientific grounds for this argument. According to a study published in Nutrition & Diabetes, consuming...
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Semaglutide 2.4 mg Could Cut Medical Costs for Some
Miriam E. Tucker November 14, 2024 0273 SAN ANTONIO — Semaglutide 2.4 mg (Wegovy) was associated with a 22% reduction in annual medical costs in people with overweight/obesity and heart failure, new research from Novo Nordisk found. The significant year-to-year reduction of more than $6500 in total medical costs suggests that the drug “can be...
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How to Stay Safe When Caring for Patients With Mpox
Hermano Rocha, MD, PhD DISCLOSURES | November 12, 2024 018 A recent webinar held by the World Health Organization (WHO) discussed safety guidance for patients and healthcare professionals involved in treating mpox cases. Speakers included Victoria Willet from the WHO’s health emergencies program, Andy Bulabula, a senior infection prevention and control technician at the Africa Centers for Disease Control...
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New mRNA Vaccine Prevents C Difficile in Mice
Heidi Splete November 05, 2024 016 A new vaccine using mRNA technology protected against first-time and relapsing Clostridioides difficile infection in animal models, according to a press release from the Perelman School of Medicine at the University of Pennsylvania, Philadelphia. In a study published in Science, an mRNA vaccine induced robust antibody responses in mice with C difficile, allowing them not only to...
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Why the early hours of the day can be especially dangerous to our health
by Weizmann Institute of Science Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.07.003 Why do asthma, heart attacks and many other health conditions tend to strike in the early hours of the morning? One possible explanation for this mysterious phenomenon has been discovered by researchers from Prof. Gad Asher’s laboratory at the Weizmann Institute of Science’s Biomolecular Sciences Department. In...
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Coffee drinking habits may greatly impact the makeup of gut biome, research suggests
by Bob Yirka , Medical Xpress Consistent global links between coffee consumption and the human gut microbiome. Credit: Nature Microbiology (2024). DOI: 10.1038/s41564-024-01858-9 A large international team of medical researchers has found that people who drink coffee regularly have much more of one type of gut bacteria than people who do not. In their study, published in the...
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RNA editing is the next frontier in gene therapy—here’s what you need to know
by Flora Hui and Guei-Sheung (Rick) Liu, The Conversation Credit: Pixabay/CC0 Public Domain The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA editing. Its aim is to treat an eye disease called wet age-related macular degeneration that causes vision loss in millions of older people worldwide. This trial marks a new...