HIV patients can cheer up, as an effective suppression of the HIV virus from a combination of three antibodies in the treatment is in sight. This was according to a new study by researchers at the Rockefeller University, revealing that the virus eventually runs out of options and dies if the method of three antibodies is tried....
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Could a tuberculosis drug help treat autism?
An antibiotic used to treat tuberculosis has the potential to alleviate the social impairments associated with autism spectrum disorder, new research suggests. Researchers suggest that the social impairments seen in autism could be treated with an antibiotic. The study reveals that the drug d-cycloserine boosted the function of an autism-related gene called PCDH10 and...
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New peptide could improve treatment for vision-threatening disease
Johns Hopkins researchers report that a new peptide holds promise for improving treatment for degenerative retinal diseases, such as age-related macular degeneration, diabetic macular edema and diabetic retinopathy. These vascular diseases often result in central vision loss as blood vessels grow into tissues at the back of the eye, where such growth should not occur....
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New drug SAK3 may offer hope to Alzheimer's disease patients
Acetylcholine is a neurotransmitter in the brain that plays an important role in controlling attention and cognition. Acetylcholine system dysfunction is believed to be one of the causes of Alzheimer’s disease (AD) and vascular dementia. Now, a new drug that could treat Alzheimer’s disease, SAK3, has been developed by a Japanese research group led by...
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A brain wide chemical signal that enhances memory
New research could lead to ways of enhancing cognitive function to counteract the effects of diseases such as Alzheimer’s and schizophrenia, as well as enhancing memory in healthy people. How does heightened attention improve our mental capacity? This is the question tackled by new research published today in the journal Cell Reports, which reveals a chemical...
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Scientists Have Unlocked the Code That Turns Genes On and Off
IN BRIEF Scientists from University of California – San Diego were able to confirm the code responsible for initiating transcription and regulation of more than half of human genes. Knowing how or why genes are turned on and off during development, as well as understanding how they respond to environmental changes, will help us find...
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New gene-delivery therapy restores partial hearing, balance in deaf mice
Investigators caution the approach is years away from use in humans Using a novel form of gene therapy, scientists from Harvard Medical School (HMS) and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both. The new model overcomes a long-standing barrier to accessing...
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What primary care providers should know about diabetic neuropathy
New guidelines from Michigan Medicine researchers and the American Diabetes Association equip physicians with better information on the condition An estimated 60 to 70 percent of people with diabetes develop some form of diabetic neuropathy, or the chronic nerve damage diabetes causes, according to the National Institute of Diabetes and Digestive and Kidney Diseases. With...
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Drug candidate stabilizes essential transport mechanism in nerve cells
NAP blocks formation of ‘tangles’ that contribute to Alzheimer’s disease Tau is a key brain protein involved in Alzheimer’s disease and other brain diseases. Aggregates of Tau known as “neurofibrillary tangles” have been associated with nerve cell death and cognitive decline. An important new Tel Aviv University study published in Molecular Psychiatry pinpoints the mechanism harnessed by...
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Study unveils new way to starve tumors to death
Blocking cancer cells’ metabolism may make treatments more effective, less toxic Unlike a healthy cell, a sarcoma cell (above) relies on environmental sources of arginine, an important protein building block. Remove environmental arginine and the cell must begin a process called autophagy, or ‘self-eating,’ to survive. A second hit to its survival pathways then kills...