Binding of the insulin analog (green) to the receptor (light blue). The receptor’s surface is shown in transparent gray. Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism. Researchers at the University of Basel were able to predict this effect based...
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The end of the filling: Alzheimer’s drug gets rid of cavities by making teeth grow back
Tideglusib, used to treat neurological disorders, could spell the end of fillings Man-made fillings can help temporarily close gaps but never restore the tooth But the drug helps to create a layer of protective material to help the gap regrow This method could also reduce the risk of infections – which fillings are prone...
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‘By moving my kidney, surgeons beat the life-threatening cancer’: A new procedure did not only save Gerry’s life, but also spared her from years of dialysis
Last April, Gerry O’Neill had a CT scan which revealed a swelling on her kidney Doctors soon discovered she had cancer, and needed dialysis and a transplant Following the new op she is back to health, and wishes to resume work as a carer Kidney cancer patients may need the organ removed and can...
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Plaque-busting plants take on Alzheimer’s and Parkinson’s
Believed by some to be a hangover cure, prickly pear extract may soon play a more significant role in helping Alzheimer’s and Parkinson’s patients as well The fight against the debilitating effects of Alzheimer’s and Parkinson’s diseases may have just gotten a new weapon from both a land-based and sea-based plant in the Mediterranean basin....
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The way you move: Tumor cells move differently than normal ones
This is a microscopic image of a tumor cell migrating through collagen. What makes cancer so deadly is its ability to move . The better that doctors can keep tumors contained and protect unaffected organs in the body, the less lethal a cancer will be. So if doctors were able to pinpoint tumor cells and...
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Researchers develop novel treatment to prevent graft-versus-host-disease
Dual inhibition of Aurora kinase A and JAK2 reduces graft-versus-host-disease, preserves the ability of the immune system to fight infections and tumor cells. Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study published as the cover story in Science Translational Medicine, Moffitt Cancer...
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Better diabetes treatment? Artificial beta cells from human kidney cells
Diagram of a HEK-beta cell. Extracellular D-glucose triggers glycolysis-dependent membrane depolarization, which activates the voltage-gated calcium channel, resulting in an influx of Calcium ions, induction of the calmodulincalcineurin signaling cascade, and PNFAT-mediated induction of insulin secretion. Researchers led by ETH Professor Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE) in Basel have...
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What a find! The virtual reality glasses that remember where you’ve left your car keys: New technology recognises objects and ‘tracks’ their whereabouts for the wearer
The new Microsoft HoloLenspromises to make losing items a thing of the past Users can hold an object up to the glasses and say ‘track this object’ When they say, for example, ‘where are my keys?’ a screen will pop up saying where it last saw them It can also flash up an alert if...
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Efficacy and safety of non-immersive virtual reality exercising in stroke rehabilitation (EVREST): a randomised, multicentre, single-blind, controlled trial
Summary Background Non-immersive virtual reality is an emerging strategy to enhance motor performance for stroke rehabilitation. There has been rapid adoption of non-immersive virtual reality as a rehabilitation strategy despite the limited evidence about its safety and effectiveness. Our aim was to compare the safety and efficacy of virtual reality with recreational therapy on motor...
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Clinical usefulness of augmented reality using infrared camera based real-time feedback on gait function in cerebral palsy: a case study
Abstract [Purpose] This study investigated the effects of real-time feedback using infrared camera recognition technology-based augmented reality in gait training for children with cerebral palsy. [Subjects] Two subjects with cerebral palsy were recruited. [Methods] In this study, augmented reality based real-time feedback training was conducted for the subjects in two 30-minute sessions per week for...