KEYTRUDA is not chemotherapy or radiation therapy—it is an immunotherapy and it works with your immune system to help fight certain cancers. KEYTRUDA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become serious or life-threatening...
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Tricky gene mutations detected by new easy-to-use DECoN software
Photo: Jan Chlebik/the ICR Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed to be identified by a separate test. The software, called DECoN, accurately and quickly detects changes in copy number of blocks of DNA called exons, by analysing sequencing data already generated to identify smaller gene...
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Blood test determines type of cancer
The scalpel-free biopsy that can pinpoint cancer: New blood test helps oncologists tell the difference between types of the deadly disease The Parsortix system can filter and collect cancer cells in a blood sample Doctors are then able to tailor the best chemotherapy to treat the disease Trials of the new device are being carried...
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Bone marrow cancer: Noninvasive detection steps closer
Researchers have for the first time shown it may be possible to detect early – or pre-fibrotic – stages of myelofibrosis noninvasively with magnetic resonance imaging. The current standard method of diagnosing the rare bone marrow cancer is through tissue analysis of biopsy samples. Myelofibrosis is a rare, slowly evolving cancer where bone marrow becomes...
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Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma
Highlights Temporal coding and noncoding transcriptomes during the muscle regenerative process Transcriptomes of satellite cells during activation, proliferation, differentiation Multidimensional chromatin maps of injured and noninjured muscle tissues Impact of epigenetic regulation and gene expression on muscle regeneration Summary Following injury, adult skeletal muscle undergoes a well-coordinated sequence of molecular and physiological events to promote...
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Can deafness be cured using stem cells? Treatment that can allow people to hear again may be ready in 10 years
Stem cell treatment for deafness Researchers have grown healthy human ear hair cells using stem cells These could one day be used to replace faulty ear cells in deaf people Patients born deaf are currently treated with an artificial cochlear implant Scientists believe they are ‘on the brink’ of a cure for hereditary deafness using...