Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Novel molecules called selective androgen receptor degraders (SARDs) may offer the next generation of treatment options for advanced prostate cancer, a new industry-sponsored study reports. The results of this research will be presented Saturday, April 1, at ENDO 2017, the 99th annual...
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Unraveling the functional diversity of longevity gene SIRT1
Two alternate forms of SIRT1 leads to discovery of how molecular specificity is encoded. While the search for elixir of life has captivated human imagination for millennia, researchers around the world have put in efforts to extend healthy lifespan and reduce the burden of morbid diseases in an increasingly aging population. Research over the...
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Scientists discover new class of anti-diabetes compounds that reduce liver glucose production
Scientists may have found a new tool for studying – and maybe even treating – Type 2 diabetes, the form of diabetes considered responsible for close to 95 percent of cases in the United States. A team of scientists from the Florida campus of The Scripps Research Institute (TSRI), Dana-Farber Cancer Institute, Harvard Medical School and the Yale...
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Doctor Turns Up Possible Treatment For Deadly Sepsis
Of the million or so Americans a year who get sepsis, roughly 300,000 die. Unfortunately, many treatments for the condition have looked promising in small, preliminary studies, only to fail in follow-up research. It’s hard not to get excited about news of a potentially effective treatment for sepsis, a condition that leads to multiple organ failure...
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Bladder drug taken by thousands is linked to dementia: Doctors warn pills should no longer be used because they raise the risk by 54%
Use of bladder drug oxybutynin has risen 31 per cent in the five years But evidence now suggests the drug’s side effects include dementia Doctors warned last night it should no longer be used because of the risks Thousands of people who take a common bladder drug are at risk of developing dementia, experts warned last...
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Anti-aging protein reverses hair loss, improves stamina in mice
These two genetically engineered fast-aging mice show the effectiveness of the peptide at manifesting hair regrowth with the mouse on the left receiving the treatment and the mouse on the right going untreated Anti-aging drug research has homed in on senescent cells in recent years. These are damaged cells that accumulate in various tissues...
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Breakthrough in ‘exercise pill’ that could help battle diabetes and obesity epidemic
A new pill could make your muscles think they’ve been exercising It targets two receptors linked to muscle metabolism and mimics exercise Researchers say the drug could help battle the obesity and diabetes epidemics A new pill is being developed that could make your body think it has exercised. American researchers are trying to target...
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Laser Activated Gold Pyramids Could Deliver Drugs, DNA into Cells without Harm
The ability to deliver cargo like drugs or DNA into cells is essential for biological research and disease therapy but cell membranes are very good at defending their territory. Researchers have developed various methods to trick or force open the cell membrane but these methods are limited in the type of cargo they can deliver...
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Astaxanthin compound found to switch on the FOX03 ‘longevity gene’ in mice
A sample containing the compound in the Allsopp laboratory. The University of Hawaii John A. Burns School of Medicine (“JABSOM”) and Cardax, Inc. (“Cardax”) (OTCQB:CDXI), a Honolulu based life sciences company, have jointly announced the results of an animal study evaluating the effectiveness of a compound that holds promise in anti-aging therapy. The Astaxanthin...
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Could diabetes drugs curb our dementia epidemic?
There may be a connection between tau proteins, which are linked to Alzheimer’s, and insulin resistance. People with lifestyle-related diabetes are at an increased risk of developing dementia and, with both conditions on the rise, scientists are scrambling to understand their connection in the hope of finding new treatments. There are 54 million people...