But research led by the University of Melbourne reported in the International Journal of Cancer, could eventually improve treatments with the identification of a protein that appears to help tumour cells become more aggressive. In Australia this year, some 3,200 new cases of Pancreatic cancer will be diagnosed, and 2,900 patients will die of the disease....
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A Novel DNA Vaccine Design Improves Chances of Inducing Anti-Tumor Immunity
PHILADELPHIA — (Feb. 24, 2017) — Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy. Cancer immunotherapy approaches, designed to harness the body’s...
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Nasal swab could help diagnose lung cancer
In the case of patients with low risk of lung cancer, the current diagnostic procedure can sometimes be invasive and unnecessary. However, new research may have uncovered a less invasive, less costly way to screen these patients. New research suggests that a simple nasal swab could accurately determine whether a patient has lung cancer. A...
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New treatment causes cancer cells to fill up with cellular ‘trash’ and self-destruct
The genomes of cancer cells—cells that do not obey signals to stop reproducing—are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins. Like all other cells, cancer cells need to be vigilant about cleaning themselves up in order to survive. Now, biologists in the laboratory of Ray Deshaies, Caltech professor of biology...
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Researcher uses wearable devices to look for clues to early Dementia and Alzheimer's
In 2014, more than 93,000 people in the United States died from Alzheimer’s disease, according to the Centers for Disease Control and Prevention. The complex nature of Alzheimer’s makes it difficult to understand and predict, until it’s too late. Boston University professor and neuropsychologist Rhoda Au is trying to change that. Through the use...
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Discovery of novel autophagy regulators for treatment of neurodegenerative diseases
Synthesised curcumin analog C1 specifically binds to TFEB and promotes its nuclear translocation, and then activates autophagy and lysosome biogenesis to degrade alpha-synuclein. A research team led by Professor Li Min, Director of the Teaching and Research Division (CMTR), and Director of the Mr and Mrs Ko Chi Ming Centre for Parkinson’s Disease Research...
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Game therapy: serious video games can help children with cerebral palsy
Cerebral palsy (CP) is the most common childhood physical disability, affecting more than 34,000 Australians, and more than 17 million people worldwide. The condition results when there is an injury to the developing brain that goes on to affect a child’s movement and posture, but can also include the senses (vision, hearing, touch) and cognition (thinking). On...
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A novel principle to mobilize neurons for brain repair
Restorative neuroscience, the study to identify means to replace damaged neurons and recover permanently lost mental or physical abilities, is a rapidly advancing scientific field considering our progressively aging society. Redirecting immature neurons that reside in specific brain areas towards the sites of brain damage is an appealing strategy for the therapy of acute brain...
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Calcium imbalance within brain cells may trigger Alzheimer's disease
New research investigates the role of calcium production in Alzheimer’s disease. The neurodegenerative process may be caused by a calcium imbalance within the brain cell. New research suggests that a calcium processing dysfunction in the neurons’ mitochondria may drive Alzheimer’s disease. Mitochondria – sometimes referred to as the “powerhouse of the cell” – are small...
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Teens with PTSD, conduct disorder have difficulty recognizing facial expressions
Adolescents with posttraumatic stress disorder (PTSD) symptoms are more likely to misidentify sad and angry faces as fearful, while teens with symptoms of conduct disorder tend to interpret sad faces as angry, finds a study by NYU’s Steinhardt School of Culture, Education, and Human Development. “Our findings suggest that exposure to stress and trauma can...