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Researchers engineer new thyroid cells

Researchers have discovered a new efficient way to generate thyroid cells, known as thyrocytes, using genetically modified embryonic stem cells. Researchers have discovered a new efficient way to generate thyroid cells, known as thyrocytes, using genetically modified embryonic stem cells. The findings, which appear in the journal Stem Cell Reports, are the first step to developing...

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New studies unravel mysteries of how PARP enzymes work

(From left) Dr. Ziying Liu, Keun Woo Ryu, Dr. W. Lee Kraus, and Dr. Xin Luo led research studies that focused on how PARP enzymes function. A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new...

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U.S. science advisory committee supports genetic modification of human embryos

Embryos could soon be edited—but there are some caveats. Ever since CRISPR—the relatively cheap and easy-to-use genome editing technique—made its way to the scientific stage, researchers have grappled with one of its biggest ethical quagmires: Its ability to edit human embryos, thereby potentially altering the DNA of subsequent generations. The question of whether to allow such a...

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Salmonella 'can kill cancer': How bacteria that cause food poisoning could be used to attack tumour cells

A genetically-altered form of salmonella is being developed to combat cancer It would kill off the tumour cells while leaving the healthy cells alone  The new strain would also help the body’s immune system target tumours  The bacteria that cause food poisoning could be used to kill cancer, medical experts said yesterday. A genetically-altered form of...

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Role of rogue protein PAK4 confirmed in pancreatic cancer cells

A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease. The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to...

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Organo-metal compound seen killing cancer cells from inside

Cancer cells seen to be targeted and killed from the inside with metal-based compound discovered by the University of Warwick The compound – Organo-Osmium FY26 – attacks the weakest part of cancer cells. FY26 is 50x more active than metal drugs used in current cancer treatments Unprecedented minute detail of cancer cells seen with nano-imaging...

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How cancers trick the immune system into helping rather than harming them

Scientists at Trinity College Dublin have discovered how certain cancers hijack the immune system for their benefit — tricking it into helping rather than harming them. While most of us are aware that our immune system protects us from infection, we may be less aware of the key role that cells of the immune system also...

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Looking at a virtual hand reduces the pain in your real hand

If you keep looking, it doesn’t hurt so much Next time a nurse sticks a needle into your arm, don’t look away: it’ll be less painful. A new study shows that we feel less pain when we are looking at our body – and that this effect works with virtual reality too. In 2009, Patrick Haggard...