Small intestinal bacterial overgrowth (SIBO) happens when elevated bacteria are in the small intestine. Excessive bacteria here can affect digestion and absorption. Image Credit: PawelKacperek/Shutterstock.com However, bacteria can offer benefits, including: Watch the webinar: Mastering Gut Health – Understanding SIBO What causes SIBO? A common cause of SIBO is normal intestinal motility dysfunction. Slow movement...
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“Bizarre” way ant venom hits a nerve: An exciting new path to pain relief
Ant venom mechanism provides new clues to how we treat pain Depositphotos View 3 Images View gallery – 3 images Insect venom may seem like an unlikely ally in the discovery of new human pain treatments, but the latest findings into the “unique” way a small ant causes us such agony is a big leap...
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Retina implant shows promise in people with severe vision loss
Science Corporation Preliminary clinical trial data show that a retina implant restored vision for people whose central visual field has holes or blurry spots, Science Corporation reported this week. Trial participants could read text and recognize playing cards when using the implant, even though they were legally blind. The results, which have not been published in a...
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New anti-obesity drug shows promise in preventing heart failure related to type 2 diabetes
Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114573 A University of Alberta pharmacology researcher has discovered that a new experimental anti-obesity drug improves diastolic heart function in mice with type 2 diabetes independent of its weight loss effects, suggesting the drug may work as a treatment to prevent the most prevalent form of heart failure in people...
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Regular exercise could reduce the severity of hangovers
Credit: Polina Tankilevitch from Pexels Most of us have been there: a night of fun turns into a morning of regret—complete with a pounding headache, nausea and fatigue. While there are plenty of supposed hangover “cures” out there—from eating a greasy breakfast to the ill-advised “hair-of-the-dog”—a recent paper suggests that regular exercise may be the key to alleviating these dreadful...
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New study challenges longstanding assumption about the cause of the genome’s most common mutation
The PER-seq measured error signature of Pol ε P286R resembles the mutational spectrum and mutational signatures of POLEd and MMRd human cancers. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01945-x A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome—one that contributes to many...
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Propelled by mechanistic insights, cancer immunotherapy breaks new ground
A better understanding of clinical outcomes, tumour dynamics and immune system interactions could lead to better outcomes. Produced by CAR-T-cell therapies have delivered transformative benefits for many cancer patients, but some recipients respond better than others.Credit: Thom Leach/Science Photo Library/Getty Crystal Mackall has seen the transformative impact of cellular therapies in paediatric oncology. She was...
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Q&A: Pathologist discusses another reason to vaccinate teens against HPV
Credit: Pixabay/CC0 Public Domain In 2006, a vaccine became available to protect against infections associated with two strains of the human papillomavirus (HPV). It was a potential game-changer: These strains cause 70% of cervical cancers, 90% of anal cancers, and about 75% of the cancers that affect the throat. Newer generations of this vaccine are generally recommended...
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Study reveals crucial role of intestinal absorption in preventing dietary-induced fatty liver disease
Researchers found that deficiency of proglucagon-derived peptides can reduce lipid uptake in the intestinal tract. Credit: Dr. Yusuke Seino / Fujita Health University The accumulation of fats in the liver is driven by high-fat diets and obesity, and is becoming an increasingly prevalent global health concern. Characterized by excessive fat accumulation in the liver, this...
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Direct Brain A-Dopamine Infusion Promising for Parkinson’s Disease
PHILADELPHIA — Continuous intracerebroventricular administration of an anaerobic dopamine formulation (A-dopamine) appears safe in patients with Parkinson’s disease (PD) and may avoid complications associated with levodopa, results from a first in-human trial suggest. A-dopamine induced a dose-dependent improvement in motor symptoms in refractory patients with severe levodopa complications and had a “really great” safety profile, said study investigator...
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