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Direct Brain A-Dopamine Infusion Promising for Parkinson’s Disease
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Direct Brain A-Dopamine Infusion Promising for Parkinson’s Disease

PHILADELPHIA — Continuous intracerebroventricular administration of an anaerobic dopamine formulation (A-dopamine) appears safe in patients with Parkinson’s disease (PD) and may avoid complications associated with levodopa, results from a first in-human trial suggest.  A-dopamine induced a dose-dependent improvement in motor symptoms in refractory patients with severe levodopa complications and had a “really great” safety profile, said study investigator...

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Cannabis Use Rising in Diabetes: What Do Endos Need to Know?

Cannabis use is becoming increasingly common among people with diabetes. A recent US prevalence study estimated that 9% adults with diabetes used cannabis in the last month, a 33.7% increase between 2021 and 2022. Nearly half (48.9%) of users were younger than 50 years. Cannabis use is also increasing sharply among those aged 65 years or older, many of...

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7 Medications That Can Make You Tired — And Why Your Antibiotic Isn’t One of Them

Written by Stacia Woodcock, PharmD | Reviewed by Christina Aungst, PharmD Key takeaways: If you’re feeling tired, it’s possible your medication is to blame. Common culprits include antihistamines, muscle relaxers, and benzodiazepines. Opioid pain medications commonly cause drowsiness, too. Acetaminophen (Tylenol) and antibiotics aren’t known to make you drowsy. But they both treat conditions (pain,...

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